IBS is not the same as inflammatory Bowel disease (IBD), a more serious condition that causes inflammation in the digestive tract and can result in severe complications. IBS It is considered a functional disorder in the way the stomach and intestines work, as there is no known reason for this relapsing gastrointestinal problem, characterized by abdominal pain, bloating, and changes in bowel habits. Perhaps Irritable Bowel Syndrome (IBS) is associated with life disorder, anxiety, stress, and practical stress, and this may be related to study stress, as medical students are considered more vulnerable than others to psychological disorder and chronic anxiety due to permanent study. Rationale: This research will be very useful because it is linked to IBS and this disease is one of the risk factors the stress, and naturally we have to ask in particular the medical students about the stress and all factors related to IBS. this will help us to determined how many medical students may affected by this disease. Literature review: According to this study A systematic review of the prevalence and risk factors of irritable bowel syndrome among medical students(Ibrahim, 2016). The results was: Sixteen studies were identified, and the prevalence of IBS among medical students ranged from 9.3% to 35.5%. The relatively high prevalence among medical students may be attributed to their special stressful learning environment. Some studies found that female gender, family history of IBS, psychiatric stress, anxiety, depression, infections, dietary factors, and sleep disorders were associated with IBS. (Ibrahim, 2016)