This is a retrospective and all‐inclusive study of ovarian histology of 74 patients who had therapeutic oophorectomy for advanced breast cancer at the Ellis Fischel State Cancer Hospital (1940‐1967). Results of the pathologic findings were itemized, coded, and correlated with all the clinical characteristics recorded. Our results showed that patients who had ovarian metastasis had higher rates of objective response than those who did not (36% vs. 11%, p = 0.02). In addition, patients with ovarian metastasis had a longer disease‐free interval and better survival after their initial mastectomy operations. However, our series is too small to show statistical significance. The coexistence of corpus luteum improved the response rates. In fact, a larger proportion of ovaries with corpus luteum contained metastasis (37% vs. 20%). Survival of patients whose ovaries had corpus luteum was much better at the fourth and fifth years after mastectomy (p = 0.03).

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