Polycrystalline Bi1−xNdxFeO3 (x=0–0.15) thin films were prepared on (111) Pt∕Ti∕SiO2∕Si substrates via metal organic deposition method. The effect of Nd dopant on the structural, electric, and magnetic properties was studied. It was found that the ferroelectric polarization and saturation magnetization of the films were enhanced by appropriate Nd doping due to the structural distortion and the suppressed cycloidal spin structure. Meanwhile, Nd-doped BiFeO3 thin films exhibited magnetic anisotropy because of the magnetocrystalline anisotropy.

To assess the outcomes of multiparametric magnetic resonance imaging (mpMRI) transperineal targeted fusion biopsy (TPFBx) under local anaesthesia. Patients and Methods We prospectively screened 1327 patients with a positive mpMRI undergoing TPFBx (targeted cores and systematic cores) under local anaesthesia, at two tertiary referral institutions, between September 2016 and May 2019, for inclusion in the present study. Primary outcomes were detection of clinically significant prostate cancer (csPCa) defined as (1) International Society of Urological Pathologists (ISUP) grade >1 or ISUP grade 1 with >50% involvement of prostate cancer (PCa) in a single core or in >2 cores (D1) and (2) ISUP grade >1 PCa (D2). Secondary outcomes were: assessment of peri-procedural pain (numerical rating scale [NRS]) and procedure timings; erectile (International Index of Erectile Function) and urinary (International Prostate Symptom Score) function changes; and complications. We also investigated the value of systematic sampling and concordance with radical prostatectomy (RP). Results A total of 1014 patients were included, of whom csPCa was diagnosed in 39.4% (n = 400). The procedure was tolerable (NRS pain score 3.1 AE 2.3), with no impact on erectile (P = 0.45) or urinary (P = 0.58) function, and a low rate of complications (Clavien-Dindo grades 1 or 2, n = 8; grade >2, n = 0). No post-biopsy sepsis was recorded. Twenty-two men (95% confidence interval [CI] 17-29) needed to undergo additional systematic biopsy to diagnose one csPCa missed by targeted biopsies (D1). ISUP grade concordance of biopsies with RP was as follows: k = 0.40 (95% CI 0.31-0.49) for targeted cores alone and k = 0.65 (95% CI 0.57-0.72; P < 0.05) overall. Conclusions The use of TPFBx under local anaesthesia yielded good csPCa detection and was feasible, quick, well tolerated and safe. Infectious risk was negligible. Addition of systematic to targeted cores may not be needed in all men, although it improves csPCa detection and concordance with RP.

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Oxygen-vacancy-related dielectric relaxations in SrTiO3 at high temperatures J. Appl. Phys. 113, 094103 (2013); 10.1063/1.4794349 Structure, magnetic and dielectric properties in Mn-substituted Sm1.5Sr0.5NiO4 ceramics J. Appl. Phys. 110, 064110 (2011); 10.1063/1.3639282Oxygen-vacancy-related dielectric relaxation in SrBi 2 Ta 1.8 V 0.2 O 9 ferroelectrics Quantum paraelectric SrTiO 3 has resulted in many investigations because of the anomalous properties. Here, using the conventional solid-state reaction method, we fabricated polycrystalline SrTiO 3 ceramics with pure cubic perovskite structure. A dielectric loss peak is observed at around 450 K and 100 Hz and it shifts to higher temperature with increasing frequency. The typical high-temperature dielectric relaxation process is confirmed to be related to the oxygen vacancies ͑OVs͒ inside ceramics. More interestingly, a Cole-Cole fitting to loss peaks reveals a weaker correlation among OVs for such dielectric materials compared with that of ferroelectrics.