in Wiley InterScience (www.interscience.wiley.com).On the analogy of the water-using networks with single contaminant, we will introduce new methodology concepts: the concentration potentials of the demand streams and those of the source streams in the water-using systems with multiple contaminants, based on the overall allocation possibility of the source streams to the demand streams. In the design procedure, the performing order of the processes is determined by the inlet concentration potentials of the processes. The processes with the lowest inlet concentration potential will be performed first. When satisfying the inlet stream of the process being performed, the source with the largest quasi-allocation amount, which is defined in this article, will be used first. A few literature examples are investigated to show the method proposed. The results show that the method proposed in this work is very simple and the freshwater consumptions of the designs obtained are very close to the minimum freshwater targets.

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Central serous chorioretinopathy (CSC) is the fourth most common nonsurgical retinopathy associated with fluid leakage. The pathogenesis is not yet completely understood, but changes in the choroid, sclera and RPE have been described associated with venous congestion of choroidal outflow. CSC can be categorised into acute, chronic, and recurrent subtypes with recent classifications of simple and complex based on the area of RPE change seen on fundus autofluorescence. A multimodal imaging approach is helpful in the diagnosis and management of CSC and secondary complications such as type 1 neovascularisation. Although spontaneous resolution with relatively good visual outcomes is common, treatment should be considered in patients with persistent or recurrent SRF. Treatment options include laser, systemic medications, intravitreal therapy, and surgery. Of these, argon laser for focal extramacular fluid leaks and photodynamic therapy of leakage identified by indocyanine-green angiography currently have the greatest supportive evidence.