No abstract

Joined at the Cs: A novel intermolecular decarboxylative C sp 3C sp 3, C sp 3C sp 2, and C sp 3Csp coupling catalyzed by CuBr and using α‐amino acids as starting materials has been developed (see scheme). Various functionalized nitrogen‐containing compounds were obtained by this method.

Take two: α‐Diazocarbonyl compounds display a diverse pattern of reactivity upon palladium‐catalyzed reaction with esters. Esters bearing an alkynyl group on the carbonyl carbon atom lead to two different CC bonds at the same carbon atom in a single operation through decarboxylation and migratory insertion, whereas aromatic and benzylic acid derivatives afford aromatic and benzylic esters bearing an O‐substituted quaternary carbon center.

A copper-catalyzed method for the synthesis of imidazo[1,2-a]pyridines with aminopyridines and nitroolefins using air as oxidation agent in a one-pot procedure has been developed. In this process, the reaction appears to be very general and suitable for construction of a variety of imidazo[1,2-a]pyridines.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.