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Climate change caused by excessive emission of greenhouse gases (GHGs) into the atmosphere has gained serious attention from the global community for a long time. More and more countries have decided to propose their goals such as Paris agreements, to reduce emitting these heat trapping compounds for sustainability. The Asian region houses dramatic changes with diverse religions and cultures, large populations as well as a rapidly changing socioeconomic situations all of which are contributing to generating a mammoth amount of GHGs, hence they require calls for related studies on climate change strategies. After pre-filtering of GHG emission information, twenty four Asian countries have been selected as primary target countries. Hierarchical cluster analysis method using complete linkage technique was successfully applied for appropriate grouping. Six groups were categorized through GHG emission properties with major and minor emission sectors based on the GHG inventory coverings energy, industrial processes, agriculture, waste, land use change and forestry and bunker fuels. Assigning six groups using cluster analysis finally implied that the approach to establish GHG emission boundaries were meaningful to develop further mitigation strategies. Following the outcome of this study, calculating amount of reduction potential in suitable sectors as well as determining best practice, technology and regulatory framework can be improved by policy makers, environmental scientists and planners at the different levels. Therefore, this work on reviewing a wide range of GHG emission history and establishing boundaries of emission characteristics would provide further direction of effective climate change mitigation for sustainability and resilience in Asia.

Saururus chinensis is a perennial herb found in the northeastern regions of Asia, including Korea, China, and Japan, and is used in traditional medicine. Studies have identified the four major constituents in Saururus chinensis water extract (LHF618®) as miquelianin (11.75 ± 0.092 mg/g), rutin (1.20 ± 0.008 mg/g), quercitrin (2.38 ± 0.389 mg/g), and quercetin (0.068 ± 0.017 mg/g). Saururus chinensis can improve the symptoms of ovalbumin- or fine dust-induced allergic pulmonary disease by suppressing the effects of WBCs and neutrophils in BALF and IgE in the serum. Saururus chinensis dose-dependently recovered morphological changes such as mucous hyper secretion (from 2.7 ± 0.46 to 0.6 ± 0.65), pulmonary epithelial cell hyperplasia (from 2.4 ± 0.55 to 0.7 ± 0.67), and inflammatory cell infiltration (from 2.3 ± 0.45 to 0.6 ± 0.43), and effectively controlled cDNA levels and protein levels of IL-13. It inhibited NF-κB translocation and COX-2 protein synthesis and suppressed the expression of PGE2. Our results show that Saururus chinensis controlled allergic pulmonary disease via the anti-inflammatory pathways, NF-κB/COX-2 and PGE2. Saururus chinensis may be a promising drug candidate against fine dust-induced allergic pulmonary disease.

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