This study aimed to investigate the clinical features of patients infected with novel coronavirus wild strains, Delta variant strains and Omicron variant strains to provide a reference for early clinical diagnosis and prognostic assessment. The demographic, clinical symptoms and ancillary examination data of 47 patients with novel coronavirus wild type strain infection, 18 with Delta variant infection and 20 with Omicron variant infection admitted to the First Hospital of Quanzhou affiliated with Fujian Medical University were collected and analyzed. The novel coronavirus wild strain and Delta strain were the predominant clinical types; patients infected with the Omicron strain were mainly asymptomatic. Fever and fatigue were the main clinical manifestations in the wild strain and Delta strain groups, whereas dry cough, nasal congestion, sore throat and fever were common clinical manifestations in the Omicron strain group. The Delta strain and Omicron variant groups had fewer comorbidities than the wild-type strain group, but no significant reduction was observed in the negative conversion time of nucleic acids. Significant differences were found in the neutrophil count/lymphocyte count ratio, lymphocyte count, eosinophil count, red blood cell count, hemoglobin level, erythrocyte sedimentation rate, C-reactive protein, prothrombin time, international normalized ratio and plasma D-dimer, PH, PaO 2 , lactic acid and albumin levels among the three groups. Patients infected with the Omicron strain in Quanzhou presented with mild symptoms of the upper respiratory tract as the primary clinical manifestation and had few comorbidities and a good prognosis; however, the negative conversion time of the new coronavirus nucleic acid was still considerably long.
The Ce0.5Zr0.5O2 solid solution with a homogeneous structure is, respectively, modulated by a hard template strategy (P-Ce0.5Zr0.5O2), the ligand decomposition method (T-Ce0.5Zr0.5O2), and the co-precipitation method (O-Ce0.5Zr0.5O2) and employed in the CO2 conversion reaction. The different catalytic performances of Ce0.5Zr0.5O2 obtained are attributed to the homogeneity degree. The T-Ce0.5Zr0.5O2 catalyst with a complete homogeneous structure presents both higher CO2 conversion and CO selectivity in the range 250–450 °C than the P-Ce0.5Zr0.5O2 catalyst with a surface Ce-rich structure and the O-Ce0.5Zr0.5O2 catalyst with a surface Zr-rich structure. Interestingly, a larger number of oxygen vacancies are observed over the T-Ce0.5Zr0.5O2 catalyst, which leads to strong CO2 and H2 adsorption ability as well as fast regeneration of hydroxyl groups. In addition, the product formation mechanisms are discussed, as analyzed by high-pressure in situ diffused reflectance infrared Fourier transform spectroscopy, where CO is thought to be produced directly by the decomposition of monodentate formate, and CH3OH generation is observed to be inclined to proceed through the following reaction route: bicarbonates/carbonates → bidentate formate → methoxy → methanol.
In order to improve the emergency decision-making and management ability of unconventional emergencies in Colleges and universities, an emergency decision-making method for unconventional emergencies in Colleges and Universities based on reinforcement learning is proposed. The function of the emergency decision-making model of unconventional emergencies in Colleges and universities is constructed, and the optimal control of the emergency decision-making process of unconventional emergencies in Colleges and universities is realized by using the queuing theory model. Based on the sub-sequence decomposition method, the reinforcement learning function is optimized. Combined with big data scheduling and the empirical mode decomposition method, the effective probability density function of emergency decision-making for unconventional emergencies in higher education is calculated, and the optimal solution vector analysis of emergency management and scheduling decision-making for unconventional emergencies in Colleges and universities is realized according to parameter estimation and quantitative optimization results. The test results show that this method has a good ability to optimize and schedule the emergency decision-making of unconventional emergencies in higher education, and has strong convergence. This method improves the emergency response-ability, and the time cost is short.
Background: A rapid increase in incidence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant occurred in Quanzhou City, Fujian Province, China, in March 2022. This study investigated the epidemiological and clinical features of SARS-CoV-2 Omicron variant (BA.2)-infected patients. Methods: Epidemiological and clinical data of SARS-CoV-2 Omicron variant infected patients admitted to three designated hospitals in Quanzhou were collected and analyzed. Results: Overall, 2,541 patients infected with BA.2, comprising 1,060 asymptomatic, 1,287 mild, and 194 moderate infections, were enrolled in this study. The percentage of moderate infections was higher in those aged ≥60 than in those aged <18 and 18-59. The median hospitalization duration was 17 (14-20) days. Among the 2,541 patients, 43.52% had a clear history of close contact. The vaccination rate for coronavirus disease was 87.92%, and the percentage of asymptomatic infections was higher in vaccinated patients than in unvaccinated patients. Moreover, 10.82% with underlying diseases, such as hypertension (5.94%) and diabetes mellitus (3.12%), had a higher percentage of moderate infections than those without underlying diseases. The three most common clinical manifestations among the patients were fever (27.47%), dry cough (25.19%), and sore throat (15.31%). The albumin-to-globulin (A/G) ratio and lymphocyte count decreased in the cases of mild and moderate infections, while procalcitonin, erythrocyte sedimentation rate, interleukin-6, D-dimer, and C4 levels increased. The pulmonary computed tomography findings for moderate infections were generally patchy and ground-glass opacities. Conclusions: Advanced age, non-vaccination, and underlying comorbid disease are high-risk factors for disease progression in Omicron variant-infected patients, while dynamic monitoring of blood routine parameters, A/G ratio, and inflammatory indicators facilitate the prediction of disease progression.
Leadership development corresponds to the focus on the individual’s success and competitiveness strategy. This is the optimal direction of the organization of attitude development because it covers two aspects of the student’s personality development: professionally-oriented and self-centric. The aim of the study is to identify and compare the leadership level in second- and fourth-year students to see dynamics of development and implementation of the leadership phenomenon in the professional and personal making up of future specialists. The task was to: (1) diagnose the existing educational impact of the university environment on the formation of leadership competencies; (2) clarify the relationship between the objective level of leadership skills development and assessment of leadership characteristics by students themselves; (3) determining tactics for further support and / or stimulation of personal and professional leadership skills of students; (4) elucidating the relationship between leadership skills and academic performance; (5) determining the universal prerequisites for the formation of leadership qualities of students. Based on the theoretical analysis of the issue, the authors developed an objective and subjective diagnostic model for leadership skills. In this study, data of the objective diagnostic technique are the key. Subjective diagnostic technique for leadership skills provides insights for problem interpretation. At the level of the first group of respondents, the average Leadership Skills Level of the second-year students was quite low and was found within the medium level. The second group of respondents consisting of the fourth-year students showed a slight but effective improvement. The Leadership Skills of this group were found at a sufficient level. Positive dynamics was revealed for all criteria of leadership skills as a result of applying objective diagnostic methods: decreased percentage of students with negative and relatively low markers of Leadership Skills Level and corresponding increase in percentage of students with positive markers of Leadership Skills Level. Further research can be organized in the direction of identifying and developing successful universal and professionally-oriented tactics for leadership development in students as part of attitude development.
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