A newly isolated strain, 38C-2-1, produced alkaline and thermotolerant alpha-amylases and was identified as Bacillus halodurans. The enzymes were purified to homogeneity and named alpha-amylase I and II. These showed molecular masses of 105 and 75 kDa respectively and showed maximal activities at 50-60 degrees C and pH 10-11, and 42 and 38% relative activities at 30 degrees C. These results indicate that the enzymes are thermotolerant. The enzyme activity was not inhibited by a surfactant or a bleaching reagent used in detergents. A gene encoding alpha-amylase I was cloned and named amyI. Production of AmyI with a signal peptide repressed the growth of an Escherichia coli transformant. When enzyme production was induced by the addition of isopropyl beta-D(-)-thiogalactopyranoside in the late exponential growth phase, the highest enzyme yield was observed. It was 45-fold that of the parent strain 38C-2-1.

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PhaseMAC (PMAC), a phase domain Gated-Ring-Oscillator (GRO) based 8bit MAC circuit, is proposed to minimize both area and power consumption of deep learning accelerators. PMAC composes of only digital cells and consumes significantly smaller power than standard digital designs, owing to its efficient analog accumulation nature. It occupies 26.6 times smaller area than conventional analog designs, which is competitive to digital MAC circuits. PMAC achieves a peak efficiency of 14 TOPS/W, which is best reported and 48% higher than conventional arts. Results in anomaly detection tasks are demonstrated, which is the hottest application in the industrial IoT scene.