Background: Transfusion-transmissible infections are well-known global health challenges. The present study is proposed to investigate the seropositivity of anti-HIV1/2, anti-HCV, HBsAg, and anti-T.pallidum among volunteer blood donors of Kosti Obstetrics and Gynecology Hospital. Methods: Our study was conducted in a cross-sectional retrospective manner. The data of donors who attended Kosti Obstetrics and Gynecology Hospital throughout 2016 to 2018 were reviewed and retrieved manually from blood bank records. Results: Out of 8139 donors, 22.52% were seropositive for serological markers of TTIs and 1.67% were seropositive for at least two serological markers of TTIs. The overall seropositivity rate of anti-HIV1/2, HBsAg, anti-HCV, and anti-T.pallidum was 1.77%, 6.07%, 1.14%, and 11.87%, respectively (p < 0.000). Anti-T.pallidum was the most frequently detected (p < 0.05) marker across all study variables. TTIs seroprevalence was significantly (p < 0.05) varied according to the age, residence, occupations, and blood groups. Notably, there was a rising trend in the rate of anti-HIV1/2 and seropositivity for more than one marker with age (p < 0.000). Regionally, rural area residents had a higher rate of anti-HIV1/2 (2.20%), HBsAg (6.31%), anti-HCV (1.42%), anti-T.pallidum (18.38%), and multiple markers seropositivity (2.28%) compared to urban areas. Between occupations, the highest rate of anti-HIV1/2 (p = 0.483), HBsAg (p = 0.003), anti-HCV (p = 0.408), anti-T.pallidum (p < 0.000), and multiple markers seropositivity (p < 0.000) were detected in farmers. Regarding the screening, we also found that the frequency of anti-T.pallidum was significantly (p = 0.003) higher in donors who carry the AB+ve blood group, whereas anti-HCV (1.83%) was more frequent in donors carry O−ve blood group (p = 0.255). As seen, anti-T.pallidum+HBsAg was the most frequently (1.22%) co-occurring markers. In contrast, anti-T.pallidum+anti-HIV1/2+HBsAg was the lowest frequency one (p < 0.000). Conclusions: The study showed an alarming rate of TTIs, which suggests the requirement for comprehensive surveillance and health education programs.

Background: Tinea capitis (TC) or scalp ringworm is common in pediatric population with reported rates of infection ranging from 4% to 15 % .T.rubrum is rarely reported in countries with a temperate climate . There is always hair loss with varying degrees of scaling and erythema [1-3]. Objectives: To identify the role of soil, plant & sewage in transmission of ringworm of scalp infection. This study was carried out on Kosti basic school students who suffering from ringworm of scalp (fungal infection) in White Nile state at Sudan in 2020. Methodology, Data Analyses and Results: Due to preservation of this fungal infection among school children in Kosti basic school students, a total of fifty specimens collected from different sources to determine the source of this infection in the area of study, twenty five students who suffering from ring worm of scalp and twenty five from soil, sewage, water and trees in the period between January – December -2020.The samples collected by scraping the scalp by surgical blade and removing the hair with needle and forceps from the peripheral lesion and gathered in filter paper and closed tightly,10% KOH was used to clarify and keratinized tissues. Trees samples were collected by washing the tree’s leaves and with all soil, sewage, water were collected into container. All samples were cultured on sabouroad dextrose agar medium for one week at room temperature. After growth, lactophenol cotton blue staining was used to identify depending on the colonial morphology under microscope and tolook for color, septate, aseptate hyphae, macro, micro conidia and spores. The results showed that there was 68% of isolates from soil, sewage, water and trees were matched to scalp isolates. The soil is significant one of these when Chi-square (X2) was used (P value = 0.027) that means, the source of infection among students may be due to soil transmission. Conclusion and Recommendation: Our results highlight the epidemiology of fungal infection of Kosti basic school students. Further studies are necessary to verify these findings considering the relatively high rate of fungal infection to cover all expected area with similar observation.