Seroprevalence of the Serological Markers of Transfusion-Transmissible Infections among Volunteer Blood Donors of Kosti Obstetrics and Gynecology Hospital

Almugadam, Babiker Saad; Ibrahim, Omer Mohammed Ali; Ahmed, Yousif Mousa Alobaid

doi:10.3390/medicines8110064

Cited by 4 publications

(5 citation statements)

References 33 publications

(158 reference statements)

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“…The prevalence was higher for HCV (2.90%) followed by HBV (1.60%), HIV (1.30%) for closing with Syphilis (0.2%). Our finding was lower when compared to study done by Yacob et al (20), Alex et al 21 , Babiker et al 22 who found 12.9 %,10.1 % and 22.52 %, successively. The reason for the lower rate of prevalence of TTI in this study compared with other studies may be due to the efficacy of the screening technique used before blood taking and also may be because of existence of different magnitude of risk factor for contracting transfusion transmitted infection.…”

Section: Prevalence Of Transfusion Transmitted Infectionscontrasting

confidence: 80%

Transfusion transmitted infections among blood donors of Kamenge Teaching Hospital blood bank in Burundi

Ntawuyamara,

Manirakiza,

Nduwimana

et al. 2024

Afr H. Sci.

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Background: The current risk of contracting a transfusion transmitted infections (TTIs) is unknown in Burundi. Objectives: The aim of this study was to assess sociodemographic profiles of blood bank donors at Kamenge Teaching Hospital, the prevalence and associated risk factors of HIV, syphilis, HBV and HCV from 2015 to 2020. Methods: We conducted a cross-sectional study including all blood donors of Kamenge Teaching Hospital blood bank. During this study, 1370 blood samples were screened for HIV, Syphilis, HBV and HCV. We calculated prevalence of TTIs and performed logistic regression to know associated risk factors. Results: Blood donors were males at 77% and 23% females. They were mostly students (54.2%). On screening, 83 blood samples (6.06%) were seropositive for at least one TTI. The overall prevalence rate of HIV, Syphilis, HBV and HCV among blood donors was 1.3%, 0.2% ,1.6%, 2.9% respectively. There was difference in distribution of the four TTIs among blood donors which is statistically significant (x2=33.997, ρ-value<0.001). Private donors were associated with a high risk of syphilis and being a first-time donor was associated with a high HBV risk factor. Conclusion: The prevalence of TTIs found still to be high; mandatory and continuous screening is necessary. Keyswords: Transfusion transmitted infections; prevalence; blood donors; blood bank; Burundi.

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Section: Prevalence Of Transfusion Transmitted Infectionscontrasting

confidence: 80%

Transfusion transmitted infections among blood donors of Kamenge Teaching Hospital blood bank in Burundi

Ntawuyamara,

Manirakiza,

Nduwimana

et al. 2024

Afr H. Sci.

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“…Also, the present rate is less than that has been stated in other previous studies in Basra province (0.2%) 7. In addition, the prevalence of HBsAg in blood donors in Basra is less than what has been reported from other countries in the region including Qatar, Jordan, Sudan, Egypt, Saudi Arabia, Lebanon, Iran and Pakistan 11 21–26…”

Section: Discussioncontrasting

confidence: 68%

“…These rates were higher in women than male, but this needs to be confirmed. Yet, these rates are less than what was found in other parts of Iraq including Karbala governate (0.76%), Anbar province in the west of Iraq (1.09%), in the Arab world and foreign countries including Qatar (0.45), Saudi Arabia (0.53), Sudan (6.6%), Pakistan (3.1%) and China (0.88%) 11 20 22 31–34…”

Section: Discussionmentioning

confidence: 80%

Prevalence and trends of transfusion transmissible infections among blood donors in Basra, Iraq

Hameed¹,

Mousa²,

Saleh³

2023

BMJ Open Gastroenterol

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BackgroundDespite saving millions of lives through blood transfusion, transfusion-transmissible infections (TTIs) still threaten the lives of patients requiring blood transfusion. Hence, screening blood donors and studying the prevalence of TTIs among blood donors may display the burden of these diseases among our population. The aim of this study was to assess the seroprevalence rates of transfusion transmitted infections among blood donors in Basra, Iraq from 2019 to 2021 as groundwork for providing safe blood transfusion in Iraq.MethodsA cross-sectional study was carried out in the blood banks in Basra, Iraq from 1 January 2019 to 31 December 2021. A total of 197 898 samples were collected and screened for hepatitis B surface antigen (HBsAg), anti-hepatitis B core (HBc), anti-hepatitis C virus (HCV) and syphilis immunologically.ResultsThe prevalence rates of seropositive of viral hepatitis for the year 2019, 2020, 2021 were as following: hepatitis B virus (HBV) rates 1.54%, 1.45% and 1.14% with significant declined trend by 26%; anti-HCV rates were 0.14, 0.12 and 0.11% with significant declined trend by 21.4%; and the syphilis rates were 0.38, 0.47, 0.36 with marked declined trend 5.3%, respectively.Of those donors showed HBV positive, 2503 (1.26%) had positive anti-HBc results, while only 173 (0.0874) showed positive test results for both anti-HBc and HBsAg.ConclusionPrevalence rates of viral hepatitis and syphilis showed a steady decline between 2019 and 2021, and these rates were much lower in Basra than in other parts of Iraq and neighbouring countries. The importance of using the anti-HBc test in the screening of blood donors was indicated in this study. These findings would contribute in improving the understanding of TTIs epidemiology and supporting health authorities controlling bloodborne diseases.

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“…Sexually transmitted infections are currently a major public health problem. In addition, many of these infections are transmissible through blood transfusions, such as HIV, hepatitis B and C, syphilis, HTLV and Chagas disease (1,2,7,8,9,11) .…”

Section: Discussionmentioning

confidence: 99%

“…Sexually transmitted infections (STIs) are currently a serious public health problem, impacting the health of the entire population in the world (1) . Many infections are transmissible through blood transfusions, also becoming widely known and publicized global health challenges (2) .…”

Section: Introductionmentioning

confidence: 99%

Serological ineptitude in blood banks: is there an association with sexually transmitted infections?

Souza,

Carvalho,

Passos

et al. 2023

J Bras Doenças Sex Transm

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Introduction: Sexually transmitted infections (STIs) are a serious public health problem, and some of these infections are also transmitted through blood transfusions. Objective: To identify publications in scientific journals in Brazil and in the world showing if there is an important association between serological inadequacy due to sexually transmitted infections traced in blood and blood products used for medical use. Methods: Systematic review of articles published from 2018 to 2023, using the LILACS, SciELO and PubMed databases, with a concomitant approach to the issues of serological disability and STI. Original studies or review articles in Portuguese, English and Spanish with Brazilian and international data were included. Editorial publications, letter to the editor, letter from the editor or comments on the subject were excluded. Results: The search found 571 articles, of which 106 (18.40%) met the inclusion criteria, that is, Serological disability and STI. In studies with international data, the prevalence of donors with hepatitis C ranged from 0.12 to 4.8%; with hepatitis B, from 1.3 to 8.2%; with HIV, from 0.0021 to 2.5%; with syphilis, from 1.73 to 2.4%; with HTLV, 0.66%; and with Chagas disease, from 0.017 to 2.76%. Among articles with Brazilian data, the prevalence of donors with seroreactive tests for hepatitis C ranged from 0.18 to 1.76%; with hepatitis B, from 0.05 to 7.9%; with HIV, from 0.03 to 0.82%; with syphilis, from 0.37 to 3.51%; with HTLV, from 0.02 to 0.3%, and with Chagas disease, from 0.8 to 0.5%. Conclusion: STIs are rarely discussed in the scientific literature in studies on serological inadequacy. In addition, a minority of articles were with Brazilian data. However, results show that STIs, despite being little discussed in the scientific literature in studies on the subject of serological inadequacy, have statistically significant percentages of seropositivity for STIs. Moreover, hepatitis C and B have a relevant seroprevalence, reaching 8.2% and 4.8%, respectively, in the international scenario. In Brazil, hepatitis B continues to occupy a prominent place with a seroprevalence of up to 7.9%. However, syphilis now holds a very important role, with a maximum percentage of 3.51%. More studies are needed for further reflection: although STIs are little addressed in studies about serological inadequacy in human blood banks, would they contribute to the maintenance and non-reduction of the general frequency of infections transmitted by blood transfusion?

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Seroprevalence of the Serological Markers of Transfusion-Transmissible Infections among Volunteer Blood Donors of Kosti Obstetrics and Gynecology Hospital

Cited by 4 publications

References 33 publications

Transfusion transmitted infections among blood donors of Kamenge Teaching Hospital blood bank in Burundi

Transfusion transmitted infections among blood donors of Kamenge Teaching Hospital blood bank in Burundi

Prevalence and trends of transfusion transmissible infections among blood donors in Basra, Iraq

Serological ineptitude in blood banks: is there an association with sexually transmitted infections?

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