Background: COVID-19 has become a health problem in the world, including in Indonesia. The high number of COVID-19 transmissions in Indonesia shows the need for massive prevention efforts. In addition to vaccination, the 5M health protocol is an effective way to reduce the number of COVID-19 transmissions. The implementation of the 5M program is influenced by several factors, including knowledge about COVID-19 and history of comorbidities.Methods: This study is an observational-analytic study that aims to analyze the influence of comorbid history during last 3 months and knowledge aobut COVID-19 disease on 5M practice in the Madiun community. 5M practices in this research include wearing masks, washing hands, maintaining distance, avoiding crowds and maintaining immunity. The research design used in this study was cross sectional with the sampling technique used was purposive sampling. Data was obtained by distributing online questionnaires to people living in the Madiun area. The population in this study is the people of Madiun, and the sample in this study is the people of Madiun who voluntarily fill out online questionnaire. The study was carried out for 7 months, starting from June to December 2020.Result: From the results of the Chi square test, it was concluded that the comorbid history and the knowledge about COVID-19 have an effect on 5M practice (comorbid history p = 0.001 and knowledge about COVID-19 p = 0.000).Conclusion : The results of this study are expected to be an input for the government in determining policies to prevent COVID-19, especially in the Madiun area.

Rambutan (Nephelium lappaceum L.) is a seasonal fruit and is a native plant from Indonesia. No wonder if it's in the rambutan season, a lot of rambutan skin trash piles up on the road. This is certainly a problem if not addressed immediately. The purpose of this PKM is to save the environment from a pile of organic waste with new breakthroughs that are worth selling in increasing the growth of the creative economy. The new breakthrough is by processing rambutan skin into SUBKUTAN. The method of implementation in this PKM includes the planning, preparation of materials and materials, manufacturing of products, stages of promotion, marketing, and the evaluation phase with an implementation period of 5 months. The results of this PKM are SUBKUTAN candied products. We have marketed SUBKUTAN products both online and offline around Madiun, then we have also worked with various pharmacies, shops, and small shops. This product has various benefits that are good for health, specifically can reduce cholesterol, besides that this product has a fairly affordable price of Rp. 15,000.00. The output of our PKM is SUBKUTAN candied products, the publication of articles in the National Scientific Journal, final report, and progress report.

Background: The proper and correct ARV therapy requires social support, especially from family and close people, in order to be able to reduce negative impacts of the infection.Methods: This study is an observational-analytic study to analyze the influence of support from close people for adherence to taking ARV drugs in PLWH in Madiun district. The research design used in this study was cross sectional with purposive sampling technique. Data was taken through interviews with respondents without giving any treatment. The sample in this study were patients who had been diagnosed with HIV positive for more than 6 months in 2018 which was randomly selected. The research location is the working area of the Local AIDS Eradication Commission (KPAD) of Madiun district. The study was conducted for 7 months, starting from June to December 2018.Result: From the results of bivariate analysis, it was concluded that the support from close people has influence on medication adherence in PLHIV (p = 0.000).Conclusion : From this research, it is expected to be an input for the government in determining health policy, especially to increase the rate of compliance with medication for PLWHA in Madiun district.