Aim: to study the features of social and metabolic indicators in adolescents with arterial hypertension (AH), to assess their informative significance and the magnitude of their contribution to the risk of developing this pathology. Design: a comparative clinical study of patients. Materials and Methods: The object of the study was adolescents aged 12–17 years (boys and girls) with and without AH. The 1st stage included the analysis of biomedical, social and metabolic indicators, the 2nd stage included an assessment of the informative significance and degree of participation of indicators as risk factors for AH. Methods: questioning, laboratory, clinical and functional, statistical. Examination program: verification of AH and its severity; association of AH with functional somatic disorders; features of biomedical, social and metabolic indicators; assessment of the significance and contribution of indicators as risk factors for AH. Results. Of the 504 examined, AH was diagnosed in 86 (17.06%) adolescents, of which 47.7% (41 people) had grade 1 AH and 52.3% (45 people) had grade 2 AH. Social risk factors for hypertension associated with family characteristics: the degree of marriage of parents — temporary cohabitation (OR = 3.36), father's profession — worker (OR = 3.14), father's education — secondary special (OR = 2.25), deviant family (OR = 2.78), family at medical and social risk (OR = 1.87). Metabolic predictors of the risk of AH: the presence of DLP (OR = 1.95), HChS (OR = 2.62), HTG (OR = 2.21), Hyper-β-CHS (OR = 1.87) and Hyper-pre-β-ChS (OR = 2.14). Conclusion. Along with traditional ones, it is necessary to identify and correct socially determined and metabolic risk factors for AH in order to optimize the diagnosis and prevention of this pathology in adolescents. Keywords: adolescents, arterial hypertension, risk factors, social factors, lipid spectrum

IntroductionAdolescent online behavior is an urgent public health problem in different countries of the world due to the possibility of developing Internet addiction.ObjectivesTo study the prevalence of different types of online behavior and Internet addiction in Siberian adolescents, depending on gender and age.MethodsDuring the period from January to May 2019, 2950 adolescents aged 11-18 years living in the urban area of Central Siberia (Krasnoyarsk) were examined, of them 1348 boys and 1602 girls. The Chen Internet Addiction Scale (CIAS) with a cut-off level of 65 points was used. Internet users are divided into three groups: Adaptive Internet Users (AIU) (27–42 points); maladaptive Internet users (MIU) (43–64 points); pathological Internet users (PIU) (score ≥ 65).ResultsThe AIU group comprised 50.3% (55.9% boys and 45.6% girls, p <0.001). The share of adolescents aged 11-14 is 52.0%, the share of adolescents aged 15-18 is 48.4% (p = 0.04). The MIU group constituted 42.9% (46.3% were girls and 38.9% boys, p <0.001). The share of adolescents aged 11-14 is 42.1%, and those aged 15-18 is 43.8%, p > 0.05. The PIU group constituted 6.8% (5.1% boys and 8.2% girls, p <0.001). The share of adolescents aged 11-14 is 5.9% and those aged 15-18 is 7.8% (p = 0.04).ConclusionsAmong adolescents in Central Siberia the prevalence of AIU consist 50.3%, MIU 42.9%, PIU 6.8%. The prevalence of PIU is more common in girls. The increase in PIU was marked in the older age group. The study was funded by RFBR project № 18-29-2203218.Conflict of interestThe reported study was funded by RFBR project № 18-29-22032\18.

Objective of the Review: To provide information on the prevalence of COVID-19 coronavirus infection in children and young people, on the negative impact of the epidemic on children and adolescents, the long-term consequences of COVID-19, and the psychosomatic status of people who have had a coronavirus infection. Key points. The COVID-19 pandemic has caused an unprecedented multi-modal (medical, professional, economic and social) crisis affecting most countries of the world, has become a factor of psychosocial disadvantage. The conducted studies give an idea of the prevalence, structure and clinical manifestations of mental disorders, disorders of the somatic and emotional status in children and young people during the epidemic, and in those who have recovered from this infection — about the features of the course of the post-COVID period. Conclusion. It is necessary to conduct longitudinal studies of the psychosomatic status of COVID-19 convalescents in the child and youth population in order to develop methods for correcting and preventing mental health disorders in this contingent. Keywords: children, students, coronavirus infection, psychosomatic status, mental health.

Приведен обзор сведений об этиологии и патогенезе неврологических проявлений у пациентов, перенесших коронавирусную инфекцию (COVID-19). Представлены данные исследований, показавших, что отдаленными последствиями со стороны центральной нервной системы являются когнитивные расстройства. Пожилые пациенты более подвержены нейропсихиатрическим и когнитивным нарушениям при COVID-19, а в случае уже имеющихся когнитивных расстройств и деменции после перенесенной коронавирусной инфекции у них наблюдается прогрессирование данных нарушений. Раннее выявление нейропсихологических проявлений у лиц, перенесших COVID-19, может снизить риск последующих необратимых нарушений и дальнейшего снижения нейрокогнитивных способностей. В качестве коррекции когнитивных нарушений у пациентов пожилого возраста могут быть рекомендованы ноотропные, метаболические, антиоксидантные средства с нейропротективным эффектом.