Reperfusion injury is still a major challenge that impedes neuronal survival in ischemic stroke. However, the current clinical treatments are remained on single pathological process, which are due to lack of comprehensive neuroprotective effects. Herein, a macrophage‐disguised honeycomb manganese dioxide (MnO 2 ) nanosphere loaded with fingolimod (FTY) is developed to salvage the ischemic penumbra. In particular, the biomimetic nanoparticles can accumulate actively in the damaged brain via macrophage‐membrane protein‐mediated recognition with cell adhesion molecules that are overexpressed on the damaged vascular endothelium. MnO 2 nanosphere can consume excess hydrogen peroxide (H 2 O 2 ) and convert it into desiderated oxygen (O 2 ), and can be decomposed in acidic lysosome for cargo release, so as to reduce oxidative stress and promote the transition of M1 microglia to M2 type, eventually reversing the proinflammatory microenvironment and reinforcing the survival of damaged neuron. This biomimetic nanomedicine raises new strategy for multitargeted combined treatment of ischemic stroke.

A new frequency response method based on a sinusoidal modulation of pressure is developed to measure gas adsorption equilibria and kinetics simultaneously. The transfer phenomena of pure N 2 and O 2 gases on carbon molecular sieve are investigated for different pressures and particle sizes by this method. The mass-transfer mechanism for N 2 can be explained by a surface barrier using a linear driving force model, but that for O 2 requires a combination of a surface barrier and micropore diffusion using a combined resistance model. Alternatively, a distribution of surface barrier resistances is introduced to take into account heterogeneity of the surface and describes the experimental data well. The linear driving force mass-transfer coefficients increase with increasing pressure but depend on the particle size only slightly. The effects of pressure on the transfer coefficients for N 2 are less pronounced than those for O 2 . The apparatus is shown to be useful in providing accurate and rapid transfer coefficient measurements and in identifying the rate-controlling adsorption mechanism.

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In this work, a direct conversion of methane in the presence of carbon dioxide using dielectricbarrier discharge plasmas has been conducted. The product includes syngas (H 2 and CO), gaseous hydrocarbons (C 2 to C 5 ), liquid hydrocarbons (C 5 to C 11+ ), and oxygenates. The liquid hydrocarbons are highly branched, representing a high octane number, while the oxygenates mainly consist of series of alcohols and acids. A detailed analysis of product distribution has been performed under variable feed conditions with different reactor configurations. At the high CH 4 /CO 2 feed ratio, the wider discharge gap (1.8 mm) is more favored for the formation of methanol and ethanol. For the production of acetic acid, the narrower discharge gap (1.1 mm) is better, especially, with the existence of after-glow zones. Conditions favored for the production of acetic acid are also good for the production of liquid fuels.

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