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Sleeping disorder is a major health threatening in high-pace modern society. Characterizing sleep behavior with pressure-sensitive, simple fabrication, and decent washability still remains a challenge and highly desired. Here, a pressure-sensitive, large-scale, and washable smart textile is reported based on triboelectric nanogenerator (TENG) array as bedsheet for real-time and self-powered sleep behavior monitoring. Fabricated by conductive fibers and elastomeric materials with a wave structure, the TENG units exhibit desirable features including high sensitivity, fast response time, durability, and water resistance, and are interconnected together, forming a pressure sensor array. Furthermore, highly integrated data acquisition, processing, and wireless transmission system is established and equipped with the sensor array to realize real-time sleep behavior monitoring and sleep quality evaluation. Moreover, the smart textile can further serve as a self-powered warning system in the case of an aged nonhospitalized patients falling down from the bed, which will immediately inform the medical staff. This work not only paves a new way for real-time noninvasive sleep monitoring, but also presents a new perspective for the practical applications of remote clinical medical service.

Chemodynamic therapy (CDT), enabling selective therapeutic effects and low side effect, attracts increasing attention in recent years. However, limited intracellular content of H 2 O 2 and acid at the tumor site restrains the lasting Fenton reaction and thus the anticancer efficacy of CDT. Herein, a nanoscale Co-ferrocene metal-organic framework (Co-Fc NMOF) with high Fenton activity is synthesized and combined with glucose oxidase (GOx) to construct a cascade enzymatic/Fenton catalytic platform (Co-Fc@GOx) for enhanced tumor treatment. In this system, Co-Fc NMOF not only acts as a versatile and effective delivery cargo of GOx molecules to modulate the reaction conditions, but also possesses excellent Fenton effect for the generation of highly toxic •OH. In the tumor microenvironment, GOx delivered by Co-Fc NMOF catalyzes endogenous glucose to gluconic acid and H 2 O 2 . The intracellular acidity and the on-site content of H 2 O 2 are consequently promoted, which in turn favors the Fenton reaction of Co-Fc NMOF and enhances the generation of reactive oxygen species (ROS). Both in vitro and in vivo results demonstrate that this cascade enzymatic/Fenton catalytic reaction triggered by Co-Fc@GOx nanozyme enables remarkable anticancer properties.

Pulse wave carries comprehensive information regarding the human cardiovascular system (CS), which is essential for directly capturing CS parameters. More importantly, cuffless blood pressure (BP) is one of the most critical markers in CS. Accurately measuring BP via the pulse wave for continuous and noninvasive diagnosis of a disease associated with hypertension remains a challenge and highly desirable. Here, a flexible weaving constructed self‐powered pressure sensor (WCSPS) is reported for measurement of the pulse wave and BP in a noninvasive manner. The WCSPS holds an ultrasensitivity of 45.7 mV Pa−1 with an ultrafast response time of less than 5 ms, and no performance degradation is observed after up to 40 000 motion cycles. Furthermore, a low power consumption sensor system is developed for precisely monitoring pulse wave from the fingertip, wrist, ear, and ankles. A practical measurement is performed with 100 people with ages spanning from 24 to 82 years and different health statuses. The discrepancy between the measured BP results using the WCSPS and that provided by the commercial cuff‐based device is about 0.87–3.65%. This work demonstrates an efficient and cost‐effective way for human health monitoring, which would be a competitive alternative to current complex cardiovascular monitoring systems.

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