Background: Dysmenorrhea is a menstrual disorder in the form of severe pain or tenderness in the lower abdomen caused by the activity of prostaglandins, during menstruation the damaged uterine lining is expelled by new compounds called prostaglandins. Intervention in adolescent girls who experience dysmenorrhea can be done by non-pharmacological techniques, namely by warm compresses and progressive muscle relaxation. Objectives: To determine the effectiveness of giving compressed warm with progressive muscle relaxation techniques to intense pain in dysmenorrhea. Methods: This study used a quasi-experimental with a pre-posttest approach, and a non-equivalent control group design. The research instrument used on the compress variable warm with progressive muscle relaxation techniques, namely SOP (Standard Operational Procedure) and pain intensity variable, namely using the NRS (Numeric Rating Scale). The population in this study found 95 female students, the samples were taken using purposive sampling, and samples in research this group collects 54 female students who are calculated using the formula slovin and drop out a formula. Results: Based on the results of statistical tests, namely the Mann Withney. Test obtained  p-value 0.187>0.05. Conclusion: In this study, there were no significant differences between the warm compress intervention and the technique of progressive muscle relaxation or both have an effect on a decrease in pain intensity in the incidences of dysmenorrhea.

Colibacillosis is a disease caused by Escherichia coli which is a normal flora bacterium of the digestive system in humans and animals. Oregano contains carvacrol and thymol which provide an antibacterial. This study was used 20 male Balb/C mice age 2-3 weeks with an average weight of 20-25 grams and were divided into 5 groups with 4 replications: negative control (KN), positive control (KP) given by streptomycin dose of 20 mg/head. E. coli dose of 3 x 109 CFU, (P1) was given by streptomycin dose of 20 mg/head, E. coli dose of 3 x 109 CFU, then given oreganoextract dose of 5 mg/head, (P2) was given by streptomycin dose of 20 mg/head, E. coli dose of 3 x 109 CFU, then given oregano extract dose of 10 mg/head, (P3) was given by streptomycin dose of 20 mg/head, E. coli dose of 3 x 109 CFU, then oregano extract was given dose of 20 mg/head. The data were analyzed by descriptive comparative. The histopathology showed epithelial cell damage or erosion caused by inflammatory cells in KP, P1, P2, and P3. In study group given oregano extract dose of 20 mg/head, P3, inflammatory cells and epithelial erosion were lower. Based on the ANOVA test of day 3 and 6 after necropsy, P1, P2, and P3 show insignificant in villi length and width of the vili (p>0,05) compared to KP. The conclusion the result of the histopathology result is epithelial erosion in group with dose of 20mg/head oregano extract was able to relieve the symptoms of colibacillosis. The conclusion of histomorphometry of the length and width of the villi at P1, P2, P3 (p>0.05) was not significantly different from the positive control.

Latar Belakang: Menstruasi merupakan perdarahan uterus yang periodik, yang terjadi kira-kira 14 hari setelah ovulasi. Salah satu keluhan yang dirasakan remaja putri adalah Dismenore primer.  Tindakan non farmakologi yang dapat diberikan kepada remaja putri yang mengalami dismenore primer adalah dengan kompres hangat dan teknik relaksasi napas dalam. Tujuan: Tujuan penelitian ini untuk mengetahui efektivitas kompres hangat dengan teknik relaksasi napas dalam terhadap intensitas nyeri dismenore pada remaja putri di Stikes X tahun 2021. Metode Metode penelitian ini menggunakan quasy experiment dengan pendekatan pre-posttest, non-equivalent control group design. Populasi pada penelitian ini berjumlah 95 remaja putri dan sampel dihitung menggunakan rumus slovin sehingga sampel berjumlah 49 remaja putri. Pengumpulan data intervensi kompres hangat dan Teknik relaksasi napas dalam menggunakan form standar operasional prosedur (SOP) dan intensitas nyeri menggunakan Numeric Rating Scale (NRS) dengan level intensitas dari skala 0-10 Hasil: Berdasarkan hasil uji statistik yaitu uji independent t-test didapatkan p-value 1,00 < α 0,05 yang artinya tidak terdapat perbedaan efektivitas yang signifikan antara kompres hangat dengan teknik relaksasi napas dalam terhadap intensitas nyeri dismenore pada remaja putri di Stikes X Tahun 2021 Kesimpulan: Tindakan Kompres hangat dan teknik relaksasi napas dalam dapat menjadi salah satu intervensi keperawatan mandiri bagi remaja putri yang mengalami dismenore primer.