Cladielloides C and D: Novel Eunicellin-Based Diterpenoids from an Indonesian Octocoral Cladiella sp. -New compounds, cladielloides C (I) and D (II), display moderate inhibitory effects on superoxide anion generation by human neutrophils. Additionally, cladielloide C exhibits significant cytotoxicity towards CCRF-CEM tumor cells. -(TAI, C.-Y.; CHEN, Y.-H.; HWANG, T.-L.; FANG, L.-S.; WANG, W.-H.; LIU, M.-C.; SU, J.-H.; WU, Y.-C.; SUNG*, P.-J.; Bull. Chem. Soc. Jpn. 84 (2011) 5, 531-536, http://dx.doi.org/10.1246/bcsj.20100348 ; Grad. Inst. Mar. Biotechnol., Natl. Dong Hwa Univ., Pingtung 944, Taiwan; Eng.) -C. Cyrus 36-182

The isolation, structures, and cytotoxicities of 5 new diterpenoids (I)—(V) are reported.

isolation, structure determination and bioactivity of the two new chlorinated briaranes, fragilide J (I) and robustolide L (II) along with the known metabolite robustolide H