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We report a case of a 48-year-old male patient with "krokodil" drug-related osteonecrosis of both jaws. Patient history included 1.5 years of "krokodil" use, with 8-month drug withdrawal prior to surgery. The patient was HCV positive. On the maxilla, sequestrectomy was performed. On the mandible, sequestrectomy was combined with bone resection. From ramus to ramus, segmental defect was formed, which was not reconstructed with any method. Post-operative follow-up period was 3 years and no disease recurrence was noted. On 3-year post-operative orthopantomogram, newly formed mandibular bone was found. This phenomenon shows that spontaneous bone formation is possible after mandible segmental resection in osteonecrosis patients.

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A 77-year-old woman applied to the Department of Oral and Maxillofacial Surgery of Yerevan Medical Center, complaining of a tumor in the left half of her face, a feeling of heaviness and asymmetry of the face. A radical removal of the tumor of the left parotideo-masticatory and mandibular regions was performed. Histopathological diagnosis: intracapsular ductal carcinoma of the salivary gland against the background of pleomorphic adenoma. The radicalism is complete. Stage III pT3 pNx pMx L1 V0 Pn0 R0. The prolonged existence of a neoplasm before a sharp increase in size suggests that a long delay in the treatment of a pleomorphic adenoma increases the likelihood of its malignant transformation. The expected results after the operation are satisfactory. Based on the results of the operation, it can be concluded that the performed surgical method is less traumatic in this diagnosis, provides a sufficient operational field of view, increases the possibility of radical tumor removal, and reduces trauma around important anatomical structures