Background Navigation systems are an effective tool to improve the installation accuracy of the cup in primary total hip arthroplasty. This study aimed to evaluate the efficacy of a computed tomography-based navigation system in achieving optimal installation accuracy of implants in revision total hip arthroplasty and to clarify the usefulness of the navigation system. Methods We conducted a retrospective study of 23 hips in 23 patients who underwent revision total hip arthroplasty using a computed tomography-based navigation system; the control group comprised 33 hips in 33 patients who underwent revision total hip arthroplasty without a navigation system. Results The average cup position with the navigation system was 40.0° ± 3.7° in radiographic abduction angle, 18.8° ± 4.8° in radiographic anteversion, and 41.2° ± 8.9° in combined anteversion; without the navigation system, the average cup position was 38.7° ± 6.1°, 19.0° ± 9.1°, and 33.6° ± 20.5°, respectively. The achievement rate of cup positioning within the Lewinnek safe zone was not significantly different between the navigation group (82.6%) and control group (63.6%). In contrast, the achievement rate of cup positioning within the Widmer combined anteversion guidelines was significantly greater in the navigation group (78.3%) than in the control group (48.0%, p = 0.029). Furthermore, outlier cases in the navigation group had a smaller variance of deviation from the optimal cup position than those in the control group did. Conclusions The results show that the use of navigation for revision total hip arthroplasty improved cup positioning and reduced the range of outliers. Improvement of cup placement accuracy influenced the installation of the stem and also improved the achievement rate of combined anteversion. Thus, a computed tomography-based navigation system is very useful for surgeons when placing the cup within the target angle in revision total hip arthroplasty.

No abstract

We herein report a case of osteomyelitis of the distal phalanx of the thumb of a 55-year-old man caused by Parvimonas micra and Fusobacterium nucleatum. Osteomyelitis often occurs in long bones and rarely occurs in the bones of fingers. In addition, osteomyelitis of the finger is frequently caused after trauma or surgery, and blood-borne infection is very rare. P. micra and F. nucleatum, normal flora of the oral cavity, are very rare pathogenic bacteria of osteomyelitis except in periodontal disease, and there are no previous reports regarding the occurrence of osteomyelitis due to P. micra and F. nucleatum in the finger bones.

No abstract

Background It is very rare for clear cell sarcomas (CCS) to arise in the bone. During diagnosis, it is important to distinguish primary CCS of bone from bone metastasis of melanoma because this difference fundamentally changes the therapeutic options. Recently, characteristic fusion genes of CCS have been detected using reverse transcription polymerase chain reaction (RT-PCR) or direct sequencing which allowed to distinguish CCS from melanoma. However, there was no study applying these analyses with positive results. In this case, we describe the use of fusion gene analysis to diagnose a primary CCS of the bone. Case presentation A 36-year-old male presented with a four-months history of left knee pain. Magnetic resonance imaging showed a lesion in the left femoral medial epicondyle. Histological examination of the biopsy specimen revealed proliferating oval or rounded cells. These cells had clear cytoplasm arranged in fascicles or compact nests with frequent deposits of brown pigment. Furthermore, immunohistochemistry analysis revealed that tumor cells were positive for S-100 protein, HMB-45, Melan-A, and SOX10. It stained negative for CD34 and BRAF v600e. Conclusively, detection of the EWSR1/ATF1 fusion gene using RT-PCR and direct sequencing confirmed that the lesion was a primary CCS of the bone. Wide-margin resection and reconstruction with a tumor endoprosthesis were performed. Conclusions Herein, we diagnosed a rare case of primary CCS of the bone by detecting EWSR1/ATF1 fusion gene using RT-PCR and direct sequencing. Since fluorescence-in situ hybridization (FISH) and RT-PCR could show false positive by mainly due to technical problems, it is better to perform direct sequencing to confidently diagnose the tumor as a primary CCS especially at very rare site such as bone.