No abstract

Assessment of glucose concentration is vital for diagnosis and treatment of diabetes mellitus. Because of the electrochemical advantages of diamond for biosensing, we fabricated a partly-oxygen-diamond solution-gate field-effect transistor to detect glucose. Partly-O-diamond was obtained from H-diamond by ultraviolet ozone treatment. Then, 1-pyrenebutyric acid–N-hydroxy succinimide ester and glucose oxidase were modified on the diamond surface. Finally, shifts of transfer characteristics were applied to determine glucose concentration. The as-prepared biosensor exhibited a wide linear response from 10-5 to 10-1 M with high sensitivity of -53 mV/log10 (glucose concentration). In addition, this biosensor showed good repeatability and stability in multiple detections.