Objective: Pleurodesis is among several treatment strategies for postoperative alveolo-pleural fistula (APF) after lung resection. Accordingly, the present study aimed to determine the influence of pleurodesis on postoperative pulmonary function.Methods: Patients who underwent anatomical segmentectomy between January 2009 and March 2020 and pulmonary function tests 6 and 12 months after initial surgery were included in this study. Differences in pulmonary function decline between patients who did and did not undergo pleurodesis were compared.Results: Among the 319 patients included, 39 (12.2%) underwent pleurodesis. Among patients who did not receive pleurodesis, there were no difference in decline of vital capacity at 6 months (À13.7% AE 1.1% vs À11.2% AE 0.7%; P ¼ .063) and 12 months (À10.7% AE 1.3% vs À9.5% AE 0.7%; P ¼ .391) after surgery between patients who had APF on postoperative day 2 and those who did not. Patients who received pleurodesis had a significantly larger decline in vital capacity at 6 months (À19.4% AE 2.4% vs À13.7% AE 1.1%; P ¼ .015) and 12 months (À16.2% AE 1.6% vs À10.7% AE 1.3%; P ¼ .010) after surgery compared with those who had APF on postoperative day 2 and did not receive pleurodesis. There were no significant differences in decline of forced expiratory volume in 1 second.

No abstract

No abstract

No abstract