ObjectiveTo investigate the effects of dilution of paramagnetic contrast agent with
iodinated contrast and xylocaine on the signal intensity during magnetic resonance
arthrography, and to improve the paramagnetic contrast agent concentration
utilized in this imaging modality.Materials and MethodsSamples specially prepared for the study with three different concentrations of
paramagnetic contrast agent diluted in saline, iodinated contrast agent and
xylocaine were imaged with fast spin echo T1-weighted sequences with fat
saturation. The samples were placed into flasks and graphical analysis of the
signal intensity was performed as a function of the paramagnetic contrast
concentration.ResultsAs compared with samples of equal concentrations diluted only with saline, the
authors have observed an average signal intensity decrease of 20.67% for iodinated
contrast agent, and of 28.34% for xylocaine. However, the increased gadolinium
concentration in the samples caused decrease in signal intensity with all the
dilutions.ConclusionMinimizing the use of iodinated contrast media and xylocaine and/or the use of a
gadolinium concentration of 2.5 mmol/L diluted in saline will improve the
sensitivity of magnetic resonance arthrography.
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