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A plausible macroscopic model of genetic regulation by feedback repression, evolved from the original formulation of Goodwin, is considered.This model has the form of a second-order non-linear dynamic system, ~ = fl(x,y), # = f2(x,y), where x(t) ~ 0 describes the mRNA which codes for the protein y(t) ~ 0, the latter acting as a repressor. Published analytical, analog, and digital studies of this model do not report the existence of any periodic solutions.A stochastic analysis has produced some irregular undamped oscillations, but these appear to be due to the stochastic elements so introduced.