Discussed changes the peripheral blood of the population of different sex living near the Semipalatinsk nuclear test site are considered. As a result, morphological changes of erythrocytes and platelets were detected.

Results of a study covering population of Maisk settlement near Semipalatinsk test site demonstrated possible thyroid diseases in 32.6% of the examinees. Predisposition to autoimmune diseases of thyroid gland (presence of antibodies to thyroid peroxidase) was revealed in 23% of the population. Increased production of stress hormone (cortisol) is characteristic for 39.4% of the females and 37.7% of the males — that is confirmed by changes in the body adaptation system of the third generation inhabitants, if ionizing radiation influence on the previous generations.

Adverse climatic and anthropogenic factors can affect the health of people living near the dried-up Aral Sea. There was modified the comprehensive assessment of inorganic chemical pollution of the environment of the village in the Zhosaly Kyzylorda region of Kazakhstan. The comprehensive assessment score included 5 categories: satisfactory, intense, critical, crisis, catastrophic. According to own research over 2014-2015 based on the mentioned assessment score, the comprehensive assessment score amounted to 41 points and showed a critical situation. In the air, there was observed the phenol content of 1.02 MAC, suspended solids - 0.5 MAC. The main part of the fine suspended solids sized of 1.5-2.5 mm, round shape, was formed in the process of condensation and evaporation of the sea and the Syr Darya River. In the dust, there was found the excess in silicon content of 2.8 MAC, iron - 1.3 MAC, zinc 1.1 MAC. As soil pollutants, there were detected sulfates - of 173.5 MAC, chlorides - 9.0 MAC, mercury - 0.56 MAC, nickel - 0.49 MAC. In drinking water, there was revealed cadmium excess of 1.3 MAC, nickel - 1.2 MAC, chlorides - 1.25 MPC, sulfates - 1.0 MAC. In the water of the Syr Darya River, there was revealed an excess in nickel - of 2.2 MAC, sulfates - 1.8 MAC, dissolved oxygen - 2.0 MAC. In the sediments of the Syr Darya river, the sulfate content accounted for 3.36 MAC and chlorides - 1.53 MAC. In the snow cover there was revealed an excess of manganese - 5.14MPC, chromium - 2.04 MAC, zinc - 1.2 MAC. In a critical situation a significant portion (30-50%) of the population may be in a state of exertion and adaptation surge, and the most susceptible part seems to be in a state of adaptation failure, characterized by an increase in incidence rate.

The authors considered changes of peripheral blood parameters in female population exposed to suspended substances (РМ10 and РМ2,5) in ambient air on ecologic disaster territory — Kazakhstan part near Aral sea. RBC changes are revealed, these signs appeared to be prevalent among the females examined, correlation links are strong between the suspended substances (РМ10 and РМ2,5) in the ambient air and the blood parameters.