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The authors studied the occurrence of admission hyponatremia and its association with selected patient and hospitalization characteristics and in-hospital mortality in a geriatric patient cohort (n = 4,123). Prevalence of admission hyponatremia was 3.5% and higher among women (4.6% vs 2.6%). In-hospital mortality was 16% for patients with admission hyponatremia versus 8.0% for patients without admission, hyponatremia. Adjusting for patient and hospitalization characteristics with a logistic regression analysis, admission hyponatremia was a significant independent predictor of mortality (RR = 1.95). Admission hyponatremia is associated with poor prognosis in the elderly hospitalized population.

Although previous research has shown that the NRP instruction improves knowledge and skill among health care personnel in the delivery room, both short-term and long-term, there has been little evidence to demonstrate NRP impact on infant morbidity. Several strategies were used in this study to control for bias and to adjust for secular trends in decreased infant morbidity during the study period. This study demonstrated sufficient support for the hypothesis that a significant improvement occurred among neonates in their Apgar score after the NRP instruction in Illinois. Empirical support is provided for the clinical effectiveness of NRP instruction.

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