Objectives: Low-dose valganciclovir prophylaxis is still under investigation in renal transplant procedures. Our aim was to assess the cost effectiveness of 450 mg versus 900 mg valganciclovir prophylaxis in kidney transplant recipients. Materials and Methods: In this prospective trial, 201 kidney transplant patients were randomized (1:1) to receive 450 mg/d (group 1, n = 100) or 900 mg/d (group 2, n = 101) valganciclovir prophylaxis for the first 6 months after transplant. Patients were studied for incidence of cytomegalovirus disease, leukopenia episodes, rejection episodes, and graft outcomes along with associated costs over 1 year. Costs (in US dollars) of treatment of rejection were also analyzed. Results: Demographic features of the studied groups were comparable. We found that the cost of cytomegalovirus care in group 1 patients was significantly lower (by 50% at 6 months; P < .001), with less leukopenia episodes (P = .04), lower doses of granulocyte colony-stimulating factor (by 30% at 6 months; P = .03), higher doses of mycophenolate mofetil (P = .04), and less rejection episodes (P = .01) compared with group 2. In group 2, there were more episodes of cytomegalovirus infection (P = .052) and BK virus nephropathy (P = .04). Graft and patient outcomes were satisfactory in both groups. Conclusions: Low-dose valganciclovir for cytomegalovirus prophylaxis after renal transplant is safer, effective and without breakthrough infection, and less costly than using the usual dose.

Background : Moringa leaf is a food of vegetables group whose utilization is still low, even though this plant has nutritional content that almost meets the nutritional needs of humans and is useful as a nutritional improvement.             Objective: This study aims to determine the physical characteristics, acceptability, and chemical composition (protein and water) of wet noodles with the addition of moringa flour.Method: This research type is laboratory research with randomized block design, treatment with addition of 0%, 3%, 6%, 9% and 12% moringa flour. Implemented in Food Technology and Nutrition Laboratory of Makassar Health Polytechnic and Health Laboratory of Makassar. Parameter analysis is physical characteristics (rendemen, elasticity and brightness), panelist acceptance and chemical characteristics (water and protein content).Results: Physically wet noodles with the addition of Moringa leaf powder has randemen average above 95%, lower than the elasticity of the wet noodles without addition of moringa leaf powder. The color of wet noodles produced is getting green along with the increasing amount of addition of moringa flour. In general, panelists receive from the texture and taste aspects. Addition of maize flour 6-12% panalis stated rather like. Wet noodles with the addition of moringa leaves flour containing water averaged 36.7%, wet noodle protein content without the addition of moringa flour by 6.39%, 3% and 9% additions respectively 6.88% and 7.44% .Conclusion:  Wet noodles with the addition of moringa flour has an average rendemen above 95%, greenness is bright, moderate elastitas. In general, panelists receive wet noodles on the addition of 3% moringa flour and slightly accept at 6-12%. Protein levels increased due to the addition of moringa flour.Keywords: Wet noodles, moringa flour

Objectives: The idea of transplanting organs is not new, nor is the disease of obesity. Obese transplant recipients have greater risk of early death than their cohorts, which is not due to increased rejection but due to obesity-related complications, including arterial hypertension, diabetes, and delayed graft function. Here, our aim was to evaluate the effects of bariatric surgery versus lifestyle changes on outcomes of moderate to severely obese renal transplant recipients. Materials and Methods: Twenty-two morbidly obese patients with stable graft function who underwent bariatric surgery were compared with 44 obese patients on lifestyle management (control group). Both groups were evaluated regarding graft and patient outcomes. Results: The studied groups were comparable demographically. In the bariatric study group versus control group, we observed that the mean body mass index was 38.49 ± 9.1 versus 44.24 ± 6 (P = .024) at transplant and 34.34 ± 7.6 versus 44.38 ± 6.7 (P = .002) at 6 months of bariatric surgery. Both groups received a more potent induction immunosuppression, but this was significantly higher in the obese nonbariatric control group (P < .05). There were more patients with slow and delayed graft functions in the same nonbariatric group. The 2 groups were comparable regarding new-onset diabetes after transplant, total patients with diabetes, and graft outcomes (P > .05). Conclusions: Bariatric surgeries are feasible, safe procedures for selected obese renal transplant recipients.

The results of the research on tempe biscuit with the substitution of moringa flour as MP-ASI did not reveal the content of protein and calcium which is a nutrient Which is important to know as fast food. This study aims to determine the content of protein and calcium in tempe biscuit formula with kelor leaf flour substitution.This research uses laboratory. Samples analyzed were 2 samples with no substitution of 0% Moringa  flour (control) and samples with Moringa flour substitution 9% (13.5 g) based on consumer acceptance. Aanalysis of proteins by khjedal method and mineral by atomic analysis spektrofothometer (AAS).          The results showed that the content of protein and calcium biscuit of tempe formula with the substitution of maize flour 9% (13.5 g) respectively by 14.9% and 38.3 mg,  Greater than non-substitution of maize leaf powder respectively 12.6% and 21.4 g.          It was concluded that the content of protein and calcium biscuit with the substitution of moringa flour is higher than that without the substitution of moringa flour. Further research on the formulation of complementari of food for breast milk  is required to balance the nutritional value in accordance with the needs of infants 6-24 months. Keywords     : Biscuits, Protein Content, Calcium Conten

Background: Nutrition problem is a public health problem that the prevention can not be done with medical approach and health service only. Nutrition problem in addition is a syndrome of poverty that closely related to the problem of food security at the household level also concerns aspects of knowledge and behavior that are less supportive of lifestyle. Puskesmas Bulurokeng Makassar City in 2016, reported that there are 45 children under five suffering from malnutrition in Bulurokeng urban village.Objectives: The purpose of community service is to assess the change of body weight (TB), height (TB) and nutritional status of children under five in the education and giving of kelor leaf meal on the daily diet of children under five in Bulurokeng Urban Village in 2016. Number of children target infants as many as 29 children, intervention carried out for 1 month.Results: The number of cadres who participated in education as many as 5 people and 29 mothers who have a toddler. But at the end of the intervention, as many as 25 children under five could be collected for analysis. Kelor flour in children under five showed significant difference of weight gain (p = 0,001), but there was no difference in height change (p = 0,41) before and after intervention. The nutritional status of children under five does not change based on body weight index by age (BB / U), height by age (TB / U) and body weight by height (BB / TB).Conclusions: It takes about 3 months of moringa flour intervention on the child's food menu, in order to appear a significant change in nutritional status in children under five.Keyword: Moringa leaf flour, nutritional status.