This paper evaluates the efficacy of the recursive least squares (RLS) in adaptive noise canceller (RLS-ANC) for fast extraction of somatosensory evoked potentials (SEPs). The RLS-ANC method was verified by simulation of electroencephalography (EEG) and Gaussian noise contaminated SEP signals at different signal-to-noise ratios (SNRs). RLS was found to converge faster than the least mean squares (LMS) algorithm in ANC, i.e. SEP extraction by RLS-ANC required fewer trials than LMS-ANC. Experimental results showed that RLS-ANC with less than 50 trials could provide similar performance in SEP extraction to those extracted by the conventional ensemble averaging with 500 trials even at SNR of-20dB.
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