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BackgroundUptake of medicinal drugs (preventive or treatment) is among the approaches used to control disease outbreaks, and therefore, it is of vital importance to be aware of the counts or frequencies of most commonly used drugs and trending topics about these drugs from consumers for successful implementation of control measures. Traditional survey methods would have accomplished this study, but they are too costly in terms of resources needed, and they are subject to social desirability bias for topics discovery. Hence, there is a need to use alternative efficient means such as Twitter data and machine learning (ML) techniques.ObjectiveUsing Twitter data, the aim of the study was to (1) provide a methodological extension for efficiently extracting widely consumed drugs during seasonal influenza and (2) extract topics from the tweets of these drugs and to infer how the insights provided by these topics can enhance seasonal influenza surveillance.MethodsFrom tweets collected during the 2012-13 flu season, we first identified tweets with mentions of drugs and then constructed an ML classifier using dependency words as features. The classifier was used to extract tweets that evidenced consumption of drugs, out of which we identified the mostly consumed drugs. Finally, we extracted trending topics from each of these widely used drugs’ tweets using latent Dirichlet allocation (LDA).ResultsOur proposed classifier obtained an F1 score of 0.82, which significantly outperformed the two benchmark classifiers (ie, P<.001 with the lexicon-based and P=.048 with the 1-gram term frequency [TF]). The classifier extracted 40,428 tweets that evidenced consumption of drugs out of 50,828 tweets with mentions of drugs. The most widely consumed drugs were influenza virus vaccines that had around 76.95% (31,111/40,428) share of the total; other notable drugs were Theraflu, DayQuil, NyQuil, vitamins, acetaminophen, and oseltamivir. The topics of each of these drugs exhibited common themes or experiences from people who have consumed these drugs. Among these were the enabling and deterrent factors to influenza drugs uptake, which are keys to mitigating the severity of seasonal influenza outbreaks.ConclusionsThe study results showed the feasibility of using tweets of widely consumed drugs to enhance seasonal influenza surveillance in lieu of the traditional or conventional surveillance approaches. Public health officials and other stakeholders can benefit from the findings of this study, especially in enhancing strategies for mitigating the severity of seasonal influenza outbreaks. The proposed methods can be extended to the outbreaks of other diseases.

PurposeMobile fitness apps (MFAs) are increasingly popular for people to promote physical activity (PA) and further enhance health status via behavioral change techniques (BCTs), but the phenomenon of users abandoning MFAs is still common. For improving users' PA and decreasing dropout rates of MFAs, this study intends to gain insights into the effects of major BCTs-based incentive factors on users' PA under MFAs context and the gender differences in their effects.Design/methodology/approachBased on self-determination theory, three major incentive factors were chosen from the perspective of self-peer-platform incentives, i.e. self-monitoring (SM), social support (SS) and platform rewards (PR). A dataset of 4,530 users from a popular mobile fitness app was collected and was analyzed using fixed effects models.FindingsThe results show that all three types of incentive factors are positively associated with users' PA. The estimated effect sizes can be ordered as: SM > PR > SS. Moreover, social support has a stronger positive impact on PA of females than males, whereas platform rewards have a weaker positive effect on PA of females than males. In addition, the results also indicate there are no significant gender differences in the effect of self-monitoring.Originality/valueThere is insufficient research on systematically examining the effects of different types of incentive factors of MFAs on users' PA in one study. This study extends the current understanding of incentive factors by simultaneously examining different incentive factors and the role of gender. The findings can also provide insightful guidance for the design of MFAs.

Obesity has been recognized as a global epidemic by WHO, followed by many empirical evidences to prove its infectiousness. However, the inter-person spreading dynamics of obesity are seldom studied. A distinguishing feature of the obesity epidemic is that it is driven by a social contagion process which cannot be perfectly described by the infectious disease models. In this paper, we propose a novel belief decision model based on the famous Dempster-Shafer theory of evidence to model obesity epidemic as the competing spread of two obesity-related behaviors: physical inactivity and physical activity. The transition of health states is described by an SIS model. Results reveal the existence of obesity epidemic threshold, above which obesity is quickly eradicated. When increasing the fading level of information spread, enlarging the clustering of initial obese seeds, or introducing small-world characteristics into the network topology, the threshold is easily met. Social discrimination against the obese people plays completely different roles in two cases: on one hand, when obesity cannot be eradicated, social discrimination can reduce the number of obese people; on the other hand, when obesity is eradicable, social discrimination may instead cause it breaking out.

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