The conflict between economic growth and environmental pollution has become a considerable bottleneck to future development throughout the world. The industrial structure may become the possible key factor in resolving the contradiction. Using the daily data of air quality from January to April in 2019 and 2020, we used the DID model to identify the effects of industrial structure on air quality by taking the COVID-19 pandemic as a quasi-experiment. The results show that, first, the impact of profit of the secondary industry on air quality is ten times higher than that of the tertiary industry. Therefore, the secondary industry is the main factor causing air pollution. Second, the effect of the reduction in the secondary industry on the improvement of air quality is better than that of the tertiary industry in Beijing. Therefore, the implementation of Beijing’s non-capital function relief policy is timely and reasonable, and the adjustment of the industrial structure is effective in the improvement of air quality. Third, PM2.5, NO2, and CO are affected by the secondary and tertiary industries, where PM2.5 is affected most seriously by the second industry. Therefore, the transformation from the secondary industry to the tertiary industry can not only solve the problem of unemployment but also relieve the haze. Fourth, the result of O3 is in opposition to other pollutants. The probable reason is that the decrease of PM2.5 would lead to an increase in the O3 concentration. Therefore, it is difficult to reduce O3 concentrationby production limitation and it is urgent to formulate scientific methods to deal with O3 pollution. Fifth, the air quality in the surrounding areas can also influence Beijing. As Hebei is a key area to undertake Beijing’s industry, the deterioration of its air quality would also bring pressure to Beijing’s atmospheric environment. Therefore, in the process of industrial adjustment, the selection of appropriate regions for undertaking industries is very essential, which is worth our further discussion.

Nowadays, innovation seems to be the inevitable choice to achieve stable economic growth. However, the negative impact of air pollution on health and economy makes air pollution an important factor in regional innovation, which deserves our discussion. The overall regional innovation level from 2014 to 2019 has an upward trend, while the overall air pollution has a downward trend during the period, which provides foundation for our research. Based on the data of 285 prefecture-level cities in China from 2014 to 2019, this paper uses the fixed effect and mediation model to verify the impact and mechanism of air pollution on regional innovation. The results show that the increase in air pollution, measured by the air quality index, significantly inhibits regional innovation. Air pollution has significant funds crowding-out effect and human capital loss effect, thereby decreasing the regional innovation level, which means innovation funds and researchers play a conductive role between air pollution and regional innovation. In heterogeneity analysis, it is found that the detrimental effect of air pollution on regional innovation is significant in eastern and central China, in large- and medium-sized cities, and in cities with poor or general air quality. It indicates that developed and large-scale regions should pay more attention to air pollution control. For polluted regions, more emphasis and endeavors are needed to address air pollution problems. Besides, the inhibitory effect is more severe on incremental innovation rather than on radical innovation, which deserves the attention of enterprises engaged in incremental innovation. Therefore, we propose that targeted environmental policies and effective measures should be developed to improve air quality in the long run. Moreover, policymakers could provide strong support for innovation grants, talent subsidies, and rewards and encourage clean technological innovation through short-term trade-offs between heavily polluting and low polluting enterprises.