Chemodynamic therapy (CDT) uses the conversion of H2O2 to ·OH triggered by Fenton‐like reactions to treat tumors, but the treatment is not complete due to insufficient intracellular H2O2 content. Photothermal therapy (PTT) uses photothermal materials for photothermal conversion to kill tumors, but it is limited by the extent of exogenous light transmission and cannot achieve satisfactory therapeutic effects. Therefore, designing a composite nanomaterial that amplifies CDT and couples it with PTT for tumor treatment is a major challenge. Herein, we designed a W‐POM NCs@HKUST‐1 nanoplatform that combines PTT and CDT and has better targeting properties. It shows high stability and photothermal conversion efficiency under the irradiation of near‐infrared light and efficiently catalyzes the generation of intracellular hydroxyl radicals, this composite material exhibits higher lethality than single therapeutic strategies. This study expands the application area of POM@MOF composite nanomaterials and provides a promising means of enhanced tumor therapy.
In this paper, we employ multifractal detrended cross-correlation analysis (MF-DCCA) to study the cross-correlation between closing price and trading volume and the multifractal characteristics of the relationship. The results show that the price, volume and price–volume cross-correlation in the rebar futures market have significant multifractal features. We find that the multifractal characteristics of price–volume cross-correlation are derived from long-term correlation and fat-tailed distribution. However, MF-DCCA cannot be used to explore the price–volume cross-correlation under different market trends (upwards or downwards). Therefore, we further adopt multifractal asymmetric detrended cross-correlation analysis (MF-ADCCA) to explore the asymmetric multifractal characteristics of price–volume cross-correlation. The empirical results show that the price–volume cross-correlation in the rebar futures market has significant asymmetric multifractality. Specifically, the asymmetry of the price–volume cross-correlation is more robust for both the price changes and the volume changes in a downtrend than that in an uptrend, indicating that the downward market tends to be more complex and riskier than the upward market in Shanghai Futures Exchange (SHFE) rebar futures market. Therefore, investors should pay extra attention to the downward market of the rebar futures and make reasonable investment strategies according to their risk appetite.
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