Sea cucumber peptide regulates tumor suppressor gene TUSC2 by targeting miR-378a-5p, which shows an inhibitory effect on tumors, and can be regarded as a new food-borne anti-tumor dietary supplement.

The present study aimed to investigate the functional properties of soybean protein isolate (SPI) treated with alkaline protease and high-speed shearing homogenization. Alkaline protease-hydrolyzed SPIs that were characterized by varying degrees of hydrolysis between 0 and 6% were treated with high-speed shearing homogenization to obtain different micro-particulate proteins. The results showed that this combined treatment could significantly reduce the particle size of SPI by markedly degrading the structure of both the 7S and 11S subunits, thereby resulting in a significantly reduced content of β-sheet and β-turn structures. The surface hydrophobicity increased considerably for samples with hydrolysis below the threshold of 2% and then declined gradually above this threshold. Furthermore, the combination of hydrolysis and homogenization significantly improved the emulsion stability of SPI hydrolysates. It also significantly improved the foaming properties of SPI. These results demonstrated that alkaline protease hydrolysis combined with high-speed shearing homogenization represents a promising approach for improving the functional and structural properties of SPI. Graphical Abstract

Sea cucumber tendon, one of the main parts of sea cucumber viscera, is widely accepted as a high nutritional food. In this study, a crude sea cucumber tendons polysaccharide (SCTP)...