Precise and on‐demand release of sufficient hydrogen (H2) to tumor sites remains a key challenge for emerging H2‐oncotherapy, and little is known about the physiological effects of “abundant” H2 on complex tumor microenvironments (TME). Here, a highly efficient and cost‐effective imaging‐guided/‐assessed H2‐therapy of tumors based on a joint electrochemo‐sonodynamic treatment (H2‐EC/SD co‐therapy) with strong “domino effect” triggered by endogenous H2 generation at tumor sites is reported to speedily eliminate tumor tissue (≤80 mm3) within 1 day. Adequate H2 is controllably generated in tumor sites through mild electrochemistry in vivo due to acidic TME by using clinical acupuncture Fe needles as electrodes. Besides starvation damage due to gas blockage/destruction of vessels, nano‐/micro‐bubbles of H2 formed in situ can elevate the tumor's internal temperature and burst vessels to further destroy the tumor under ultrasound irradiation. Remarkably, vulnerable homeostasis of TME is disturbed as H2 also participates in the physiological activity of tumor cells, leading to tumor dysfunction. Last but not least, the body's inflammatory response to cancer is reduced after the treatment, which is beneficial for the body's immune system during post‐treatment recovery. Based on all of these merits, the H2‐EC/SD co‐therapy provides a potentially safe and viable therapeutic strategy for future clinical applications.

Two-dimensional layered materials are considered ideal platforms to study novel small-scale optoelectronic devices due to their unique electronic structures and fantastic physical properties. However, it is urgent to further improve the light–matter interaction in these materials because their light absorption efficiency is limited by the atomically thin thickness. One of the promising approaches is to engineer the plasmonic environment around 2D materials for modulating light–matter interaction in 2D materials. This method greatly benefits from the advances in the development of nanofabrication and out-plane van der Waals interaction of 2D materials. In this paper, we review a series of recent works on 2D materials integrated with plasmonic environments, including the plasmonic-enhanced photoluminescence quantum yield, strong coupling between plasmons and excitons, nonlinear optics in plasmonic nanocavities, manipulation of chiral optical signals in hybrid nanostructures, and the improvement of the performance of optoelectronic devices based on composite systems.

Magnetic Fano resonance provides a potential opportunity to control both linearity and nonlinearity of light for their low radiation loss and near-field enhancement. Previous investigations have demonstrated its significant enhancement of nonlinearity in a plasmonic structure and the 2D materials coupled to it. In this work, the enhancement of second harmonic generation (SHG) of hybrid bismuth halides at the important communication wavelength of 1550 nm with a magnetic Fano dip is theoretically studied. To this end, a hybrid system composed of two asymmetric silver square split rings (SSRs) and this chiral perovskite film is designed. The simulation results show that magnetic Fano-like resonance is induced at the destructive interface of two magnetic modes in the SSR dimer, which can be inherited to hybrid bismuth halides, thereby leading to the increase of four orders of magnitude in its SH near-field enhancement factor. With a peak intensity of 0.16 GW cm−2, the composite structure features a high SHG conversion efficiency of up to 1.6 × 10−3 at the Fano resonance position. By rotating the polarization angle of fundamental optical excitation, the emitted SHG signal is switched on–off. Our research provides a valuable thought for enhancing the nonlinear optical process of the perovskite films by coupling the magnetic modes.