Controlling the complex dynamics of active colloidsthe autonomous locomotion of colloidal particles and their spontaneous assemblyis challenging yet crucial for creating functional, out-of-equilibrium colloidal systems potentially useful for nano- and micromachines. Herein, by introducing the synthesis of active “patchy” colloids of various low-symmetry shapes, we demonstrate that the dynamics of such systems can be precisely tuned. The low-symmetry patchy colloids are made in bulk via a cluster-encapsulation-dewetting method. They carry essential information encoded in their shapes (particle geometry, number, size, and configurations of surface patches, etc.) that programs their locomotive and assembling behaviors. Under AC electric field, we show that the velocity of particle propulsion and the ability to brake and steer can be modulated by having two asymmetrical patches with various bending angles. The assembly of monopatch particles leads to the formation of dynamic and reconfigurable structures such as spinners and “cooperative swimmers” depending on the particle’s aspect ratios. A particle with two patches of different sizes allows for “directional bonding”, a concept popular in static assemblies but rare in dynamic ones. With the capability to make tunable and complex shapes, we anticipate the discovery of a diverse range of new dynamics and structures when other external stimuli (e.g., magnetic, optical, chemical, etc.) are employed and spark synergy with shapes.

The assembly of active and self-propelled particles is an emerging strategy to create dynamic materials otherwise impossible. However, control of the complex particle interactions remains challenging. Here, we show that various dynamic interactions of active patchy particles can be orchestrated by tuning the particle size, shape, composition, etc. This capability is manifested in establishing dynamic colloidal bonds that are highly selective and directional, which greatly expands the spectrum of colloidal structures and dynamics by assembly. For example, we demonstrate the formation of colloidal molecules with tunable bond angles and orientations. They exhibit controllable propulsion, steering, reconfiguration as well as other dynamic behaviors that collectively reflect the bond properties. The working principle is further extended to the co-assembly of synthetic particles with biological entities including living cells, giving rise to hybrid colloidal molecules of various types, for example, a colloidal carrousel structure. Our strategy should enable active systems to perform sophisticated tasks in future such as selective cell treatment.

Colloidal particles with surface patches can self-assemble with high directionality, but the resulting assemblies cannot reconfigure unless the patch arrangement (number, symmetry, etc.) is altered. While external fields with tunable inputs can guide the assembly of dynamic structures, they encourage particle alignment relative to its shape rather than the surface patterns. Here, we report on the synthesis of metallodielectric patchy particles and their assembly under the AC electric field, which gives rise to a series of structures including two-layer alternating chains, open-brick walls, staggering stacks, and vertical chains that are directed by the patches yet reconfigurable by the field. The configurations of the assemblies (e.g., the chains) can be further switched between a rigid and a flexible state emulating the conformations of polymers. Our work suggests that, for directed colloidal assembly, the particle complexities (patches and shapes) can be coupled with the external manipulations in a cooperative manner for creating materials with precise yet reconfigurable structures.

components combine excellent electronic performance and good stretchability, [8,9] but their delicate structures are prone to mechanical damage. Transfer printing of serpentine electronics onto elastomer films could enhance their overall structural robustness. [10,11] However, the dense polymer substrate may hinder water and vapor transport arising from biological tissues, causing potential issues for wearable applications. [12][13][14][15] In addition, poor conformability of dense films on non-developable 3D surfaces is another limitation. [16,17] Kirigami-inspired structures have recently emerged as promising candidates for stretchable electronics. [18][19][20][21][22][23]