Endometriosis is a chronic, progressive, relapsing estrogen-dependent disorder characterized by the growth of tissue structure and function similar to the endometrium outside the normal mucosa of the uterine cavity localization. Endometriosis is found in 10-15% of women in reproductive age and it is one of the main causes of pelvic pain syndrome and infertility. Mechanisms of the development of endometriosis and related pathological pain impulses are still poorly understood and therapeutic approaches do not always have a sufficient effect; in this connection, the study of the pathogenesis of endometriosis and endometriosis-associated pain currently is perspective. Identification of significant factors of angiogenesis, lymphangiogenesis, and neurogenesis in the external genital endometriosis will promote the development of non-invasive early diagnosis and pathogenetic therapy.

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The study included 154 patients and tested in the examination and treatment FGBU “NIIF St. Petersburg”, Russia's Health Ministry in 2011, in connection with suspected genital tuberculosis. All patients fulfilled clinical and laboratory examination with bacteriological, immunological and histological methods. Comparative analysis revealed that the sensitivity Diaskintest ® exceeds the sensitivity of the Mantoux test with 2 TE (66.7% vs. 55%, respectively), but specificity was lower Diaskintest (75% and 80%, respectively). Consequently, it is advisable to use Diaskintest and Mantoux test with 2 TE complex for early diagnosis of genital tuberculosis, and the correct formation of groups at risk for the development of a specific inflammation of reproductive organs in women who are subject to patient care