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Poster abstracts deep endometriosis were submitted to US and MR so as to correlate the findings. In both methods the sizes, location and the extension of the lesions were analyzed. Results: US detected a total of 40 lesions meanwhile MR detected 53 lesions in the pelvis. The comparative study between US and MR has not shown significant statistical difference (P > 0, 19% and P > 0, 14%, respectively). Taking into consideration rectosigmoid junction, MR has detected one lesion (5.6%) meanwhile US has indicated four lesions (22.2%). In the rectum lesions, US has detected eight (44.4%) and MR detected seven lesions (38.9%). Conclusions: US presented better results in the rectosigmoid junction and in the rectum; however it has detected a smaller number of lesions in the pelvis. In the global comparative analyses between US and MR in the detection of the lesions, there was no significant statistical difference.Supporting information can be found in the online version of this abstract. Objectives: To research the peculiarities of uterus tissual blood flow during steroid therapy of adenomyosis. Methods: 66 patients with adenomyosis, diagnosed according to clinical symptoms, transvaginal ultrasonography with color Doppler imaging (CDI) and loop biopsy of myometrium, were treated with combination of 30 mkg of ethinylestradiol and 2 mg of dienogest for 3 months daily and then for 9 months under contraception regimen, the menstrual blood volume, dysmenorrhea, the quantity of blood flow loci in myometrium were meanwhile observed. The patients were divided in two groups according to treatment results: effective -60, ineffective -6. Results: In the first 6 months of treatment, the menstrual blood volume was reduced significantly (P < 0.01) in both groups, and dysmenorrhea was obviously relieved. According to the data of CDI the quantity of color loci in middle and internal layers of myometrium per unit area during the treatment in the first group was reduced by the 3 month (P < 0.01) and didn't change during the treatment and for 3 months after cessation of therapy. In the second group recurrences of haemorrhage and/or dysmenorrhea served as indications for surgical treatment in 2 cases 8-10 months since the beginning of treatment, in 4 cases in 3 months after the cessation. In this group the reduction of myometrium vascularisation level wasn't registered in 5 cases in the whole course of observation. The difference in quantity of blood flow loci in 3 and 6 months after the beginning of the treatment between groups was significant (P < 0.05). Conclusions: Continuously high level of myometrium vascularisation according CDI data can serve as a predictor of ineffectiveness of steroid therapy of patients with adenomyosis.

1 Федеральное государственное бюджетное образовательное учреждение высшего образования «Кубанский государственный медицинский университет» Министерства здравоохранения Российской Федерации, ул. Седина, д. 4, Краснодар, Россия, 350063. 2 ГБУЗ «Краевая клиническая больница №2», ул. Красных Партизан 6/2, Краснодар, Россия, 350012. АННОТАЦИЯ Цель. Определить значимые маркеры ультразвукового исследования и магнитно-резонансной томографии в диа-гностике глубины инвазии ворсин хориона в миометрий у беременных с рубцом на матке после операции кесарева сечения. Материалы и методы. Ретроспективно было изучено 68 беременных с 28-ю по 32-ю неделю гестации с рубцом на матке после кесарева сечения и расположением плаценты по передней стенке матки. В зависимости от гистологиче-ской верификации степени врастания плаценты беременные были разделены на 4 группы. Осуществлялась эхогра-фическая и МРТ оценка нижнего маточного сегмента и выделение наиболее значимых УЗ и МР критериев врастания плаценты. Полученные результаты исследования в последующем обрабатывались по алгоритмам факторного ана-лиза с расчетом информативности каждого критерия и определением прогноза врастания ворсин хориона. Результаты. В результате в I группе беременных сумма баллов составила числовое значение в пределах 0-0,9 усл. ед., во II группе -1-3 усл.ед., в III группе -сумма баллов составила 3,1-5,0 усл.ед., в IV группе -5,1-7,0 усл.ед. В III и IV группах обращает внимание факт наличия сочетания признаков. В III группе сочетание 2 признаков встречалось в 65% случаев, 3 признаков -у 25% беременных. Заключение. Наиболее информативным ультразвуковым параметром врастания плаценты было определение ве-нозных лакун в супрабазальной части плаценты (0,42), при МРТ исследовании оценка стенки мочевого пузыря (0,45).Чувствительность и специфичность УЗИ составили 86,2% и 84,8%, МРТ исследовании 96% и 94,4% соответ-ственно. Federation, Sedina str.,4, Krasnodar, Russia, 350063. ²SBHI «Regional Clinical Hospital №2», Krasnich Partisan str., 6/2, Krasnodar, Russia, 350012. ABSTRACT Aim. To define significant ultrasound and magnetic resonance imaging markers in diagnostics of the depth of chorion invasion in myometrium in pregnant women after Cesarean section was carried out. Materials and methods. 68 pregnant women from 28 to 32 gestation weeks with Caesarian scar and placenta on the front wall of uterus were retrospectively studied. Pregnant women were divided into 4 groups depending on histologic verification of placenta invasion depth. MRI and ultrasound assessment of the lower uterine segment was carried out and the most significant US and MRI markers of placenta accreta were distinguished. Subsequently, the received results of the research were processed by algorithms of factor analysis with calculation of informativeness of each marker and with determination of the forecast of placenta accreta.

Background. Wounds of various aetiology are among the most frequent traumatic injuries. A prospective route to improve treatment of this nosology is the development of novel or advancement of the already on-stage dressing materials.Objectives. A comparative experimental assay of novel chitosan-based wound dressings in the healing of soft tissue wounds of different genesis using ultrasound to control biodegradation of the developed dosage form.Methods. Soft tissue wounds were modelled in experimental animals, conventional and lineage male rats, 275 (± 25) g body weight, and male rabbits, 2,900 (± 150) g weight, using a proprietary methodology (Patent on invention RU No. 2703709 dated 23 August, 2018).Two wound dressing samples selected as most promising and applicable in large-volume soft tissue aseptic wounds were tested in the final step of experiment. Ultrasound imaging of the model wound area during the sample material biodegradation was used to control the wound process in more detail. At all steps of experiment, animal models were handled in compliance with GOST 33044-2014 “Principles of Good Laboratory Practice”.Histomorphological assays were carried out with common protocols. Variation statistics was used for the data analysis, including the mean (M) and standard mean error (± m) estimation. The level of statistical significance was p < 0.05.Results. The animal assays and comprehensive evaluation of the obtained data revealed a high healing efficacy of chitosan-based wound coatings. The analyses of wound dressing samples have confirmed their predesigned properties: scaffold stability, capillarity, biodegradability and matrix capacities for the carried drug delivery.Additionally, ultrasound was proved effective to estimate dynamics of the coated wound healing and biopolymer biodegradation processes.Conclusion. The developed chitosan-based wound dressings exhibited efficacy in an experimental model of the soft tissues wound process.The use of ultrasound to study dynamics of the wound process and coating biodegradation provided an adequate congruence between the imaging and tissue histomorphology data, as well as the structure and properties of coating material.

льтразвуковая диагностика закрепила свое лидирующее место при диагностике патологий сонных артерий. В статье представлен обзор современной отечественной и зарубежной литературы об объеме информации, которая может быть получена при помощи цветного дуплексного сканирования сонных артерий. Даны определения наиболее часто встречающимся патологиям сонных артерий (атеросклероз и патологическая извитость). Приведены современные представления об атеросклеротических бляшках, методы измерения степени сужения сосуда и классификации атеросклеротических бляшек. Так же приведены современные представления о нестабильности атеросклеротических бляшек. Представлены наиболее распространенные и современные классификации деформаций сонных артерий, критерии их локальной гемодинамической значимости.Ключевые слова: атеросклероз сонных артерий, стеноз сонных артерий, нестабильная атеросклеротическая бляшка, долихоартериопатия, деформация сонных артерий.