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A single transcranial electrostimulation of rats results, as does acute stress, in a fourfold elevation of plasma corticosterone, whereas after a course of several electrostimulations plasma corticosterone is not elevated and a threefold rise in plasma [~-endorphin is recorded. Rats that undergoing a course of transcmmal electrostimulations and then subjected to an immobilization stress do not show any rise in plasma corticosterone.

Lactate dehydrogenase activity, crystallogenic and initiator characteristics of biological substrates were evaluated by enzymological and crystalloscopic analysis of rat serum and urine. Changes in these characteristics of biological media in combined thermal injury were shown. This approach is effective for evaluation of the metabolic status in rats with experimental burn disease.