The article continues the tradition of writing scientific reviews concerning achievements in the field of pediatric gastroenterology, laid down by the leaders of Russian pediatrics and neonatology - A. V. Mazurin, N. G. Zernov, B. G. Apostolov, A. A. Baranov, V. F. Uchaykin, G. V. Rimarchuk, Yu. G. Mukhina, P. L. Shcherbakov, S. V. Belmer, I. Yu. Melnikova and others. The article discusses the origins, development and successes of modern Russian pediatric gastroenterology. Important in the diagnosis of diseases of the digestive system in children, beginning at an early age (up to 3 years), along with laboratory methods, have played methods of medical intrascopy. The main achievements in the study of diseases of the esophagus, stomach, intestines, hepatobiliary system, pancreas are analyzed. Prospects for the development of pediatric gastroenterology as an independent area of pediatrics are being advanced.

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Адрес для корреспонденции: Запруднов Анатолий Михайлович-д.м.н., проф. кафедры педиатрии с инфекционными болезнями у детей факультета дополнительного профессионального образования Российского национального исследовательского медицинского университета им. Н.И. Пирогова 117997 Москва, ул. Островитянова, д.1

The article discusses interactions between medications (Ms) and food. The influence of Ms on the processes of absorption of the essential food ingredients, vitamins, macro- and trace elements in the gastrointestinal tract is analyzed. The significance of the malabsorption syndrome, antibiotic-associated diarrhea as cause of the impaired nutritional status is emphasized. Simultaneously, food products are able of altering the pharmacological effect of some most common drugs. Administration of Ms depending on food intake is discussed. The importance of taking into consideration the influence of foods and theirbiologically active substances on the pharmacokinetics of Ms in the body is pointed out.