Current knowledge of the pathogenesis of acne determines the need for early use of drugs with antiinflammatory activity.Aim: to determine the effectiveness of monotherapy using Adaklin cream in the treatment of acne in adolescent children.Material and methods. All adolescents with acne of light and moderate severity were examined to determine the dermatological index of acne (DIA), determine the level of production of sebaceous glands, testing the parents of patients. Monotherapy was performed using Adaklin cream.Results. 60 patients with acne were under observation. Formation of clinical remission was registered in 78.33 % of adolescents. A good tolerability of the therapy and a high level of compliance were noted.Conclusion: the high efficacy and tolerability of therapy with the use of Adaklin cream in adolescents with acne was stated.

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Actuality. High incidence of atopic dermatitis and its association with systemic pathology determine the need of broad treatment options on the base of the modern data on pathophysiology of the disease. Aim of the study. Analysis of the clinical efficacy of the complex therapy with application drug Kestine® and probiotic FlorOK. Materials and Methods of the study. 55 patients with atopic dermatitis with mild and medium severity stages were examined and treated. The SCORAD Index and the Prurindex were used for assessment of AD severity; H2- test was used for evaluation of the digestive system function. Study results. It was stated high clinical efficacy of the complex therapy with application drug Kestine® and probiotic FlorOK accompanied by fast arrest of the itch.