Федеральное государственное бюджетное образовательное учреждение высшего образования «Кубанский государственный медицинский университет» Министерства здравоохранения Российской Федерации, ул. Седина, д. 4, Краснодар, Россия, 350063. АННОТАЦИЯ Цель. Изучение динамики синдрома внутрибрюшной гипертензии и ишемического реперфузионного синдрома, обусловливающих абдоминальный сепсис у больных с распространённым перитонитом.Материал и методы. Изучено течение заболевания у 136 больных с распространенным гнойным перитонитом. Выделено 4 группы пациентов по уровню внутрибрюшной гипертензии. Ретроспективная оценка тяжести течения инфекции проводилась в соответствии с базовыми позициями «Sepsis-3». Внутрибрюшное давление контролиро-валось системой Uno Meter Abdo Pressure® Kit. Уровень лактата в периферической крови определялся хромато-графическим методом.Результаты. В 3 и 4 группах (n=74), абдоминальный сепсис был у 47 пациентов, у 27 пациентов был септиче-ский шок. Внутрибрюшная гипертензия снижалась у 29 пациентов назоинтестинальной интубацией, у 45 пациентов декомпрессионной лапаростомией. Ишемический реперфузионный синдром развился в 58,6% и в 48,9% случаев соответственно. Динамика уровня лактата крови и органной недостаточности была более продуктивна у больных с лапаростомией. Летальность составила 17,2% и 15,6% соответственно.Заключение. Тяжесть реперфузионных нарушений при перитоните зависит от степени выраженности внутри-брюшной гипертензии и внутрикишечной гипертензии, сроков их существования, способа и скорости декомпрессии брюшной полости и кишечника. Прогрессирование абдоминального сепсиса и отрицательная динамика синдрома «ишемии-реперфузии» в послеоперационном периоде у больных с распространенным перитонитом увеличивает летальность. Federation, Sedina str.,4, Krasnodar, Russia, 350063. MANIFISTATIONS OF ABDOMINAL SEPSIS IN PATIENTS WITH DIFFUSE PERITONITIS Federal State Budgetary Educational Institution of Higher Education Kuban State Medical University of the Ministry of Healthcare of the Russian ABSTRACTAim. The study of the dynamics of the syndrome of intraperitoneal hypertension and ischemic reperfusion syndrome, which cause abdominal sepsis in patients with diffuse peritonitis.Materials and methods. The course of the disease was studied in 136 patients suffering from diffuse purulent peritonitis. Four groups of patients were identified according to the level of intra-abdominal hypertension (WSACS). A retrospective assessment of the severity of the infection was carried out in accordance with the basic positions of "Sepsis-3". The intraabdominal pressure was monitored by the Uno Meter Abdo Pressure® Kit. The level of lactate in peripheral blood was evaluated by chromatographic method.Results. In groups 3 and 4 (n=74), abdominal sepsis was in 47 patients, in 27 patients there was a septic shock. Intra-abdominal hypertension was reduced in 29 patients by naso-intestinal intubation, in 45 patients -by decompression laparostomy. Ischemic reperfusion syndrome developed in 58.6% and in 48.9% of cases, respectiv...
Aim. To consider the possibility of the diagnosis of a rare small bowel tumour complicated by small bowel obstruction and small bowel bleeding, as well as the surgical treatment of this pathology using a minimally invasive surgical approach.Results and discussion. The authors present a clinical case of associated complication of a gastrointestinal stromal tumour (GIST) of the small intestine in a 48-year-old patient. The patient was admitted to a surgical clinic with small bowel obstruction, episodes of intestinal bleeding and anaemia. The diagnosis was determined using CT enterography. In line with the current trends for minimally invasive surgery, minimally invasive laparotomy was performed drawing on the CT mapping of the anterior abdominal wall. The last stage involved in the morphological verification of GIST, which employs a standard procedure of IHC testing, revealed a malignant GIST, spindle cell variant. The verified histotype of a small intestinal tumour provides the opportunity to choose the necessary variant of adjuvant chemotherapy, as well as to improve general and relapse-free survival.Conclusion. Minimally invasive operations can be performed in the complicated course of GIST due to the biological properties of this pathology (absence of lymphogenic metastasis and infiltrative growth) without decreasing five-year survival rate. The use of CT helps make a topical diagnosis and plan minimally invasive surgical treatment.
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