Ischemic heart disease (IHD) is the world's major cause of death. It presents clinically as myocardial infarction and ischemic cardiomyopathy and is also known as coronary artery disease. To define LVEF percentage in CAD patients. This cross-sectional study was done retrospectively by collecting data from the database of "Scientific Research Institute of Cardiology and Internal Diseases" Almaty, Kazakhstan during 2020. IHD was confirmed in clinical, angiographic and other lab findings with TTE used for detection of LVEF. A sequential non-random sampling technique used SPSS for statistical analysis. Conventional echocardiography showed that there were significant differences in LVEF percentage in patients based on age and gender. The number of female and male patients who have preserved LVEF was 66.4% and 54.7% accordingly, 21.6% of females and 22.1% of males had Mid-range LVEF and 12.1% of females and 23.3% of males had decreased LVEF (P-value = 0.001). The mean of LVEF was (55.8% ±11.79). Maximum and minimum of EF were 84%, 12% respectively. We discovered that EF was moderately lower in male patients than in females in the sample. When compared to patients without a history of IHD, those with IHD history showed more significant EF deterioration. IHD patients with low EF appeared to be at high risk of Hypertension and infarction with decreased HDLc.