In conclusion, this study confirms that laparoscopic repair of large hiatal hernias is effective and durable over a long period of time. Reinforcement of crura repair with ProGrip™ mesh is safe and can prevent anatomical recurrences.

Мета. Покращити діагностику та результати лікування хворих з пухлинами прямої кишки шляхом застосування тран- санальної ендоскопічної мікрохірургії і вивчення «сторожових» лімфатичних вузлів. Матеріали і методи. За період з 2009 по 2017 р. у клініці трансанальні ендоскопічні операції виконані 115 хворим у віці від 29 до 82 років. У 92 пацієнтів була тубуловорсинчата аденома прямої кишки, із них у 26 гістологічним дослі- дженням видалених пухлин виявлено малігнізацію (TisN0M0). У 23 пацієнтів до операції виявлено ранній рак прямої кишки Т1–2N0M0.  Результати. У строки спостереження від 12 до 60 міс рецидив виявили у 2 (2,2%) хворих з аденомою і у 3 (13%) з раком прямої кишки. Рецидив раку виник у хворих, які відмовилися від хіміотерапії та променевої терапії. Висновки. Ідентифікація і прицільне дослідження «сторожових» лімфатичних вузлів при раку прямої кишки умож- ливлює вірогідну (чутливість=0,89, специфічність=0,99) оцінку стадії захворювання і застосування адекватної схеми комбінованого і комплексного лікування пацієнтів.

Intraoperative diagnosis of «sentinel lymph nodes» with objective to select the surgical procedure in gastric and uterus cancers

Objective. Studying of possibility of application of a self-fixing mesh ProGrip™ while plasty performing for large hiatal hernias (HH).Маterials and methods. In the investigation 144 patients, ageing 30 – 78 yrs old, owing HH with square 10 - 20 сm2, took part. The patients were divided into two groups. Group I consisted of 71 patients, to whom crurorhaphy with additional strengthening of the sutures, using a self-fixing mesh ProGrip™ was peformed. Group II consisted of 73 patients, in whom sutures of crurorhaphy were not strengthened by the mesh implant. Dynamical follow-up in patients was conducted in 3, 6, 12, 24, 36, 48 and 60 mo after the surgical treatment.Results. Average duration of the operation in patients of Group i and Group II did not differ essentially – (94 ± 12) and (92 ± 15) min, accordingly (p > 0.1). In late terms of follow-up the HH recurrence have occurred in 3.2% in the Group I patients and in 21.5% - in the Group II patients. The quality of life index in patients of Group I, in accordance to questionnaire SF-36, was trustworthily better, than in patients of Group II (p < 0.05).Conclusion. The mesh ProGrip™ application while doing plasty of large HH permits to lower the recurrence rate significantly and to improve the operative interventions results essentially.

Objective. Studying of velocity of prevalence of luminescent dye indocyanine green along lymphatic vessels in the large bowel surgery. Materials and methods. Estimation of procedure for coloring of tumoral substrate and lymphatic vessels while performance of oncological operations was conducted. We performed laparoscopic resection of sigmoid colon in 7 patients, suffering tumors, and anterior rectal resection in 5 patients, having tumors of upper ampullary part of rectum, using indocyanine green dye. Results. In Group I, consisting of 7 patients, surgical technique of no touch manipulations on the tumor before transection of feeding vessels (NTIT–operations) was applied, and in Group II, consisting of 5 patients, the tumor mobilization was done primarily. Application of indocyanine green dye helped a lot to establish localization and prevalence of the process in rectum. Conclusion. Application of fluorescent dye indocyanine green on tumoral substrate before doing ligation of feeding vessels raises possibility of the complication occurrence, consisting of the cancer cells dissemination in abdominal cavity. While performing laparoscopic procedures in resection of the large bowel tumors it is expedient to ligate the feeding vessels primarily, with secondary manipulation– to dissect and mobilize the tumoral substrate.