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Elucidation of the medico-social portrait of contemporary children has revealed a twofold increase in the rate of psychosomatic pathology, a 50-80% increase in the level of neurotization, and a 40% decrease in the level of intellectual development relative to normal values typical of their age. Development of methods of automatic prophylactic screening and prognosis of adequate adaptation of schoolchildren is an urgent problem. New objective methods for testing of cognitive functions in schoolchildren are of particular interest. The goal of this work was to describe the application of computer-assisted psychodiagnostic systems to diagnosis of cognitive disorders in schoolchildren 8-15 years of age. Using these systems, we obtained quantitative age-related characteristics of the prerequisite of high level of intellect development in children with high scores. The results of comparison of the tests of standard reference tests of cognitive functions (CF: perception, attention, memory, psychomotor and mental activities) in successful schoolchildren with such results in schoolchildren with low scores would reveal parameters correlating with difficult learning and reduced quality of life.

1 Российский национальный исследовательский медицинский университет им. Н.И. Пирогова МЗ РФ, 2 Научный центр здоровья детей МЗ РФ, 3 Первый Московский государственный медицинский университет им. И.М. Сеченова, Москва, Российская Федерация В обзоре последовательно рассматриваются различные аспекты метаболизма железа у детей в норме и при наличии инфекци-онного процесса. Особое внимание уделено проблеме сочетания инфекций с анемией/железодефицитными состояниями, не-инфекционным факторам дефицита железа и анемии в детском возрасте, а также новым подходам к диагностике нарушений метаболизма железа (включая исследование таких показателей, как гепсидин, ферропортин, растворимый трансферриновый рецептор, гипоксия-индуцибельный фактор, транспортер двухвалентных металлов и т.д.). Кратко описаны основные зарубеж-ные исследования с использованием маркеров метаболизма железа при инфекционно-воспалительных заболеваниях у детей различного возраста. Подчеркивается неоднозначность и дискутабельность нарушений метаболизма железа у детей на фоне инфекций и состояний, сопровождающихся воспалением. Ключевые слова: анемия, воспаление, дети, диагностика, инфекция, железодефицит, метаболизм железaThe Iron Metabolism in Children is Normal also at Infectious Diseases The authors consistently consider various aspects of iron metabolism in children and in pediatric patients with accompanying infectious process. Special attention is attributed to the problem of combined infections with anemia/iron-deficiency states, non-infectious factors of iron deficiency and anemia in childhood, as well as to novel approaches to diagnostics of iron metabolism disorders (including the studies of markers such as hepcidin, ferroportin, soluble transferrin receptor, hypoxia inducible factor, divalent metals transporter, etc). Foreign investigations incorporating novel iron metabolism markers in pediatric patients of various ages with infectious/inflammatory disorders are concisely described. The ambiguity and disputability of iron metabolism in pediatric patients against the background of infections and conditions, accompanied with inflammation are stressed.