The work is focused on the study of characteristics of sedimentational self-purification from radioactive and conservative chemical pollutants in Sevastopol Bay waters. Using data on the distribution of ⁹⁰Sr, ¹³⁷Cs, 239,240 Pu, ²¹⁰Po, Hg, ΣPCB₅, and ΣDDT in the surface (0-5 cm) layer of bottom sediments in different areas of the bay, it is shown that the concentrating ability of living and inert matter concerning contaminants (characterized by the concentration coefficient) is one of the major parameters in realization of biogeochemical mechanism of water self-purification. The effect of sedimentation processes is aimed at maintaining the radionuclides and chemical homeostasis of marine ecosystems by the Le Chatelier-Brown principle. Hg, ΣPCB₅ and ΣDDT are shown to be the main pollutants of Sevastopol Bay waters at present.