No abstract

Acute nasopharyngitis is the most common reason for visit a doctor, usually benign, self-limited disease. It is also characterized by a high frequency of complications in children and nonspecific symptoms that require special care from the doctor when examining patients. The clinical and social significance of acute nasopharyngitis is due to their high prevalence, and inadequate treatment leads to a protracted course or to a transition to a chronic one. The relevance of this problem adds to the presence of a large number of various drugs, but not many drugs have evidence-based effectiveness. In the treatment of acute nasopharyngitis local drugs are very important. The drug is a silver proteinate agent with broad antibacterial anti-inflammatory activity. The drug is used to treat infectious rhinitis. This article evaluates the use of a new form of the silver proteinatedrug, the drug is available in the pharmacy, easy to use, long shelf life. This article describes the place of silver proteinate among drugs that help to relieve the symptoms of acute nasopharyngitis and provides data on its effectiveness, safety and features of use in children. The drug can take a worthy place among topical drugs due to its high efficiency in the treatment of acute rhinitis and its possible use at any age.

Инфекционно-воспалительные заболевания глотки -одни из наиболее распространенных патологических процессов в человеческой популяции. Необходимость адекватной диагностики и назначения рационального эффективного лечения при данной патологии обусловлены важной ролью гло тки в жизнедеятельности организма и высоким риском развития осложнений. В подавляющем большинстве клинических случаев не требуется назначения системных препаратов, исполь-зуется топическая терапия. Однако в свете новых данных о значимости микробиотических популяций (микробиом), соз-дающих функциональный барьер между окружающей средой и слизистой носоглотки, актуальным становится применение в комплексе лечебных мероприятий при болезнях глотки препаратов, оказывающих не только антисептическое и противо-воспалительное, но и биоценозсберегающее действие. В свете этого перспективными представляются препараты на осно-ве лизоцима -фермента, являющегося естественным антисептиком для человеческого организма. Представителем таких средств является комбинированный препарат Лизобакт ® , выпускаемый фармацевтической компанией «АО Босналек». Лизобакт ® обладает выраженным противовоспалительным, иммуносберегающим и антисептическим действием и являет-ся эффективным средством лечения заболеваний глотки у пациентов различных возрастных групп.

Polypoid rhinosinusitis (PRS) is a form of chronic rhinosinusitis (CRS), which is a heterogeneous group of pathological conditions based on a chronic inflammatory process of the nasal cavity and paranasal sinuses (PNS), leading to polypoid tissue formation. In most cases, T2-inflammation underlies the pathogenetic mechanism of PRS. In the presence of T2-associated conditions, the course of PRS is usually severe. The main aim of PRS treatment is to control symptoms, prolong the recurrence-free period, and restore the aeration of the PNS. The basic therapy of PRS involves the use of intranasal glucocorticosteroids (InGCS), which have a nonspecific anti-inflammatory effect by acting on different points of the pathological inflammatory process. The level of evidence for the use of InGCS is Ia: the drugs are included in Russian and foreign clinical guidelines for the treatment of polypoid rhinosinusitis. InGCS have high topical activity at low steroid doses. Mometasone furoate has an important place among this group of drugs because of its high efficacy, long-lasting therapeutic effect and optimal safety profile. The drug is officially registered for the treatment of PRS. Long-term use of mometazone furoate has been clinically observed to cause almost no atrophic nasal mucosal changes. It can be administered as monotherapy and in combination therapy over long periods of time in all phases of the treatment of PRS.

The study analyzed the clinical effect of the surgical treatment of 25 patients with Meniere’s disease, 20 of which underwent endolymphatic sac drainage and five of which underwent vestibular neurectomy via translabyrinthine approach. The methods of surgical treatment are described and their advantages and disadvantages. The authors proposed an algorithm for the surgical rehabilitation of patients with Meniere’s disease.