The prevalence of risk factors for cardiovascular diseases and the electrophysiological state of the myocardium in male patients with somatoform dysfunction of the vegetative nervous system was studied. Among the risk factors, the leading positions were taken by stress, low physical activity and smoking. A method has been developed for diagnosing prenosological changes in the electrophysiological state of the myocardium associated with the tension of the regulatory systems in male patients with somatoform dysfunction of the vegetative nervous system in order to identify prenosological conditions and increased risk of the cardiovascular disease. The correlation between the sum of points according to the developed method and indicators characterizing the state of the sympathetic section of the vegetative nervous system and the electrophysiological state of the myocardium have been proved. The threshold score for risk factors for the cardiovascular disease, corresponding to the presence of prenosological changes in the electrophysiological state of the myocardium in male patients with somatoform dysfunction of the vegetative nervous system is 8. The diagnostic sensitivity of the method in male patients with somatoform dysfunction of the vegetative nervous system with a threshold score of 8 was 80 %, specificity-70.8 %.