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It should be noted that only 2 classes were observed a systematic reduction of the primary disease for 10 years-a class of diseases of the digestive system and diseases of skin and subcutaneous tissue. While the reverse trend in 2010 compared to 2006 to 2.8% in 2015 compared to 2010 and 10.3% was observed in the class of diseases of the digestive system and 10.3 percent respectively, and 29.7% in the class of diseases of the skin and subcutaneous tissue. In grade 5 had a decline of primary disease in the last 5 years (2010-2015): infectious and parasitic diseases of 9.9%, diseases of musculoskeletal system and connective tissue (27,5 per cent), congenital anomalies of development of 17.7%, neoplasms-in 1,5 times, diseases of the circulatory system-2,4 times. Due to the diferent growth rates and reduce the incidence of disease classes in dynamics for 10 years has changed and its structure, rank place. So, in 2006, the irst seven places were occupied by classes: 1st-diseases of the respiratory system 2-digestive organs, 3-diseases of the skin and subcutaneous tissue, 4-ediseases of the musculoskeletal and connective tissue, 5-e-eye disease, 6th disease of the nervous system 7 diseases of the genitourinary system certain conditions of the perinatal period. In 2015 there was a change of rank the irst 7 places-1 e-diseases of the respiratory system, 2 diseases of the nervous system, infectious and parasitic diseases, 3-e-a separate condition of perinatal period, 4th-diseases of the ear, 5-e-eye disease-6th-diseases of the musculoskeletal system and connective tissue 7 diseases of the genitourinary system and diseases of the digestive system. In dynamics for 10 years the most stable ranking places occupy diseases of respiratory organs (1 place), infectious and parasitic diseases(2nd place), eye disease (5th place), diseases of the genitourinary system (7th place). Other classes of diseases in dynamics for 10 years has been a space or leading (diseases of the nervous system, certain conditions of the perinatal period), or low (diseases of the digestive system, diseases of the musculoskeletal system and connective tissue). Thus, for 10 years, saved adverse trends in the growth of General and primary morbidity of children 0-14 years, which as a whole increased by 46% and 45.5%, respectively. The increased incidence is mainly due to the class leading rank places: diseases of the nervous system, diseases of the ear, diseases of the respiratory system, certain conditions of the perinatal period, infectious and parasitic diseases, which in 2015 is a signiicant frequency (80,9%) of the entire spectrum of diseases. Among certain classes there is a decrease in indicators (diseases of the digestive system; diseases of the skin), although the structure of these classes take up only about 5%. Conclusions. Overall, both components of morbidity (General and primary) have a tendency to increase in terms of time, what determined the ratings, the level and the structure of classes. The data obtained can be used in programs of preventive...

Амурский медицинский журнал №3 -4 (15 -16) 2016plasms, diseases of the nervous system, diseases of the eye and adnexa, diseases of the ear and mastoid process, diseases of respiratory organs diseases of digestive organs, diseases of the genitourinary system, injury and poisoning).In the dynamics of primary disease marked not stable indicators in 9 categories: neoplasms, diseases of blood and blood-forming organs and disorders of immune mechanism, endocrine, nutritional and metabolic disorders, diseases of the eye and adnexa, diseases of the circulatory system, diseases of digestive organs, diseases of the musculoskeletal system and connective tissue congenital malformations, diseases of the skin and subcutaneous tissue.It should be noted that growth of primary morbidity among adolescents in the classes of diseases of the nervous system, blood circulatory system and digestive system, indicates the unused reserves of primary prevention outpatient care, family and educational institutions.The analysis of morbidity rate in adolescents has allowed to deine in traic year on its leading rank place. So, 2006-2015 I ranked place was occupied by diseases of the respiratory system which accounted for 31.5 to 44%. of the diseases; rank II place -diseases of the musculoskeletal system and connective tissue, the proportion of which is of 20.0-9.9% of all morbidity. Diseases of the genitourinary system rank III take place, but share in common their incidence is much lower -7,6%-8,7%.Diseases of the endocrine system with 4-th place in 2006 moved to 5th place in 2015, losing to diseases of the eye and adnexa. Diseases of the digestive system, which occupies in the structure of morbidity in 2006. 5 place 10 years moved to 6th place.At the same time, diseases of the nervous system with 6-th place in 2006 become to 5th place in 2015, on the 7th place in 2006 -diseases of the eye, in 2015 -diseases of the endocrine system, and is a disease of the circulatory system, whose share is 4.1 %.In the far East region ranking places in 2010 took 6 classes: diseases of respiratory (34.3 percent), diseases of the digestive system (17.2 per cent), injury and poisoning (10.8 per cent), diseases of the eye and adnexa (7,0%), diseases of the musculoskeletal system (6%), diseases of the genitourinary system (5.2 percent), the amount of the contribution in the total morbidity amounted to 80.5%.In the city of Blagoveshchensk in 2010 ranked the leading places were: diseases of the respiratory system (39,4%), diseases of the musculoskeletal system and connective tissue (15.7%), eye disease (7,6%), diseases of the genitourinary system (7.0 percent), diseases of the circulatory system (5.8 percent), diseases of the nervous system (4.8%), amount of contribution in the total incidence rate was 80.3%.At the same time, starting in 2010, there was a feature of the structure of diseases in adolescents of the city of Blagoveshchensk in comparison with indicators of the far Eastern region and in Russia as a whole, where the leading ranks had classes respiratory ...

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Summary: Epidemiological studies indicate a high prevalence of vitamin D deficiency among children and adult population in different countries [1][2][3][4][5][6][7][8]10]. In connection with the numerous studies of foreign authors, which proved the adverse effects on the body vitamin D: the development of autoimmune and inflammatory disorders, cancer (mammary, pancreas, prostate gland, intestine and colon), heart failure, hypertension, myocardial infarction, diabetes mellitus, obesity. In connection with the urgency of the problem of insufficient content of cholecalciferol in the blood of children, a survey of 229 children of different ages. This study is a fragment of a multicenter, prospective, cohort, pharmacoepidemiological studies assessing the provision of child population younger age group vitamin D in the Russian Federation "SPRING". The results of study of vitamin D metabolites in serum of healthy children from 3 to 6 years, adolescents aged 15-17 years living on the territory of Amur region. These results allow to speak about necessity of revision of existing methodological recommendations taking into account modern approaches to the prevention and treatment of deficiency with different degrees of severity of vitamin D in children and adolescents.