The determination of factors associated with progression of cervical cancer is important, both for a recurrence risk assessment and for determining optimal treatment tactics. Previously, we showed the prognostic value of different types of tumor microvessels (MVs) in gastric and breast cancer. The object of this research was to study the morphology and clinical significance of different tumor microvessels in early cervical cancer. A total of 65 archived paraffin blocks of patients with I-IIA stages of squamous cervical cancer were investigated. Samples were stained with Mayer hematoxylin and immunohistochemically using antibodies to CD34, podoplanin, HIF-1a, and Snail. The eight types of tumor MVs differed in morphology were identified. It was established that only the dilated capillaries (DСs) with weak expression of CD34, the contact type DCs, the capillaries in tumor solid component, and the lymphatic vessels in the lymphoid and polymorphic cell infiltrates of tumor stroma are associated with clinical and pathological characteristics of early cervical cancer. Preliminary results also suggest that a combination of fragmentation in tumor solid component and the contact type DCs may predict a recurrence of early cervical cancer. Given the small number of cervical cancer recurrences, the predictive significance of the described markers requires a more thorough examination.

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The article is devoted to the presentation and study of the work of the Museum Zaeltsovka (branch) of the Museum of Novosibirsk and highlighting the features of museum of local history of a new type. In Russian and foreign museology the formation of a new type of local museum is associated with the dynamics of socio-cultural transformation the expansion of the concept of heritage an increase in the number of communicative practices in the field of presentation of heritage to society. Expansion and analysis of the empirical base that characterizes the activities of regional city museum which have significant potential and resources of museums of local history of a new type is acquiring significant scientific and practical significance. Already at the stage of organization the museum of the Zaeltsovsky district of Novosibirsk was aimed at working with the local community developing the regional and local historical and cultural heritage. For the period from 2013 to 2018 a scientifically based thematic and chronological exposition was created and modernized reflecting the history and modern development of the Zaeltsovsky district. The communication model of the "Museum Zaeltsovka -the socio-cultural center of the metropolitan area" has been successfully introduced. The information resource under the motto "Zayeltsovka 5/5" as a basic trend of the museum indicated the activity in the priority positions of the museum of local history. Implementation of the interdepartmental project "We are the fellow countrymen" broadcasting the regional and local identity of the Novosibirsk region exhibition and museum-pedagogical activities is of actual and promising importance for functioning of Zayeltsovka as a museum of local history of a new type, work on the development of the historical and cultural heritage of the region. Keywords: Museum "Zaeltsovka"; the city of Novosibirsk; a museum of local history of a new type; the socio-cultural center of the metropolis district; exposition; the project "We are fellow countrymen"; exhibition activities; the development of the historical and cultural heritage of the region.

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