Our goal was to develop objective criteria for early diagnosis of acute hematogenous osteomyelitis (AHO) of bones of the hip joint (BHJ)) in children. For the differential diagnosis between AHO and the reactive coxitis (RC) we examined a total of 93 children (61 AHO BHJ and 32 RC cases). AHO BHJ patients are characterized by a higher degree of endogenous intoxication when compared with RC patients. CT allows diagnose AHO BHJ before the appearance of radiological signs (starting from 3 days from the onset of the disease) in the bone tissue and can be used to differentiate AHO BHJ from RC. These features allow using these parameters as objective criteria for the differential diagnosis in children with acutely developed pain in hip joint area

<p>АНАЛИЗ РЕЗУЛЬТАТОВ ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ ЭХИНОКОККОЗА ПЕЧЕНИ</p><p>Целью работы было улучшение результатов хирургического лечения эхинококкоза печени и качества жизни оперированных больных путем оптимизации существующих и разработки новых методов эхинококкэктомии <br />из печени. исследование основано на изучении результатов применения различных вариантов оперативных вмешательств при лечении 305 больных с эхинококкозом печени. Все пациенты за последние 10 лет (2005–2015) прошли лечение во II клинике самаркандского государственного медицинского института. Послеоперационные осложнения были отмечены у 35 (11,5 %) больных, послеоперационная летальность отмечена в 1 (0,3 %) <br />случаях. рецидив эхинококкоза имел место у 17 из 236 наблюдавшихся больных в отдаленном периоде (77,4 %). результаты хирургического лечения эхинококковых кист печени во многом зависят от ифференцированного подхода к выбору адекватного способа оперативного лечения, учета морфологической формы эхинококковой кисты и соблюдения принципов апаразитарности и антипаразитарности. В отдаленном периоде рецидив эхинококкоза наблюдали у 2,9 % больных, оперированных по поводу осложненного эхинококкоза, а также у 4,2 % больных, отказавшихся от химиотерапии в послеоперационном периоде.</p>

Our aim is to evaluate the possibilities and effectiveness of computed tomography (CT) in a complex of the examination of patients with chronic recurrent hematogenic osteomyelitis of tubular bones. The effectiveness of the CT use in a complex of examination of 60 chronic recurrent hematogenous osteomyelitis of tubular bones in patients aged from 7 to 22 years was analyzed in the work. CT, in contrast to the survey X-ray, made it possible to more accurately determine the true dimensions of the destructive process in the affected bone. In all cases, CT surpassed traditional radiography in the identifying small sequesters promoting chronic inflammation and causing a persistently recurrent course of the disease. With the help of CT, delineated foci of destruction, i.e., intraosseous abscesses, were clearly visualized, whereas with the plain X-ray this substrate was not detected. The obtained data show the high resolution of the CT, to provide with complete information on pathomorphological changes in the bone. This seems extremely important for planning treatment tactics and choosing the amount of surgical intervention.

In this study, in the Screening Center of the Samarkand Region over the period of 2010-2015 there were screened 416,672 pregnant women from the risk group (parents are close relatives, the age of a pregnant woman over 35 years, spontaneous abortions in early pregnancy, the use of medications early in pregnancy, hereditary diseases in relatives, etc.). On average, 69,445.3 pregnant women were examined during the year. For the mentioned 6 years, 1053 (2.5 ‰) malformations of the fetus were detected. Anomalies of the brain and skull predominated in the structure of antenatal lesions of the brain - 428 cases (40.6%), multiple defects -154 (14.6%), abdominal and abdominal defects - 163 (15.5%), spine and spinal cord - 103 (9.8%), the developmental defects of the genitourinary system -70 (6.6%) and defects of other systems were found less frequently, in 5%. The prevalence rate of anorectal malformations in the general structure of antenatal lesions was 2.6% (27), and 16.6% - in the structure of abdominal and abdominal malformations. According to data from these surveys, there were revealed sensitivity, specificity, general accuracy and the role of sonography for the detection of anorectal defects in the antenatal period.

A comparative study in two groups of children received a complex of restorative therapy during the rehabilitation period, with measures for correction of intestinal biocenosis, neurometabolic therapy, and immunotherapy with Viferon and children receiving the immunomodulator T-activin only showed the significant efficacy of the integrated approach in rehabilitation. In addition, a relatively fast positive immunological effect is achieved, a good tolerance of the drug Viferon, a non-invasive route of administration and the absence of adverse responses with the immunorehabilitation method described allow us recommending this drug in the complex of immunoresponsive measures in infants who have had suffered from sepsis.