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In recent years, a consensus has grown across the European Union that the acquisition of transversal skills—including foreign language and entrepreneurial skills—is key to the success of learners in their personal and professional life. The CRADLE teaching methodology for primary school teachers is the first teaching methodology to simultaneously foster both of these skill sets, employing a cross-curricular, activity-based, pupil-centred, exploratory teaching and learning approach based on a linear four-step process inspired by Design Thinking with problem-solving and designing solutions in mind. This article discusses the implementation of the CRADLE teaching methodology in six primary schools in three European countries. Based on an analysis of project plans, lesson observations and teachers’ feedback during the pilot stage of the methodology, we are able to demonstrate that the methodology is a flexible tool for developing students’ knowledge and skills. The observed results provide evidence of increased pupil interest and involvement, successful acquisition of foreign language and communication skills (accuracy and fluency in speaking, vocabulary development, ability to express opinions and ideas, answer questions and understand instructions) and emerging entrepreneurial skills such as self-efficacy, creativity, valuing ideas, taking initiatives, planning and management, and working with others.

The development of markets for scientific and technological initiatives in modern Russia requires the transformation of educational processes. Highly qualified specialists with "hard skills" and "soft skills" are more in demand. The application of practice-oriented approaches to educational activities ensures the development of these competencies. Mathematics studies are not limited by a specific discipline. Some aspects of mathematics are involved in other profession-related disciplines, too. The practical activities of undergraduates at agricultural universities include a lot of experimental work and analysis of the results. The teachers can simulate this situation in the educational process with the help of business games, which allows the increase of students' proactive behavior and motivation in the educational process and identification of the talented youth. With the purpose of improvement of the effectiveness of the educational process, several disciplines should be joined together in the business game. For agricultural universities, the most acceptable example of discipline convergence is a combination of mathematics, genetics and biology. The authors found out that the use of business games in the educational process has improved the quality of knowledge of students in the disciplines up to 70-80%. The average performance of students in mathematics was 70%, which is 5% higher than before the introduction of this teaching strategy in the educational process.

Background: Covid-19 vaccination has started in the majority of the countries at the global level. Cancer patients are at high risk for infection, serious illness, and death from COVID-19 and need vaccination guidance and support. Guidance availability in the English language only is a major limit for recommendations’ delivery and their application in the world’s population and generates information inequalities across the different populations. Methods: Most of the available COVID-19 vaccination guidance for cancer patients was screened and scrutinized by the European Cancer Patients Coalition (ECPC) and an international oncology panel of 52 physicians from 33 countries.Results: A summary guidance was developed and provided in 28 languages in order to reach more than 70 percent of the global population. Conclusion: Language barrier and e-guidance availability in the native language are the most important barriers when communicating with patients. E-guidance availability in various native languages should be considered a major priority by international medical and health organizations that are communicating with patients at the global level.

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