Bovine pericardium samples modified with ethylene glycol diglycidyl ether, designed for surgical correction of congenital heart defects and large blood vessels, were studied by scanning electron microscopy, X-ray diffraction, IR spectroscopy, and differential thermal analysis. It was found that the initial samples of pericardium, before implantation, contain sites of disorganization of the collagen matrix, fragile fracture of collagen fibrils and destruction of the interstitial membranes promoting the penetration of immunocytes into the deep layers of the pericardium. Ossifying calcification with amorphized hydroxyapatite deposition and bone tissue formation as well as multiple erosions and hypertrophic proliferation in the endothelial membrane were detected in the implantation pericardium samples.

<p>This publication presents the clinical observation in a paediatric patient with haemangioma of the left stomach. The effectiveness of surgical treatment of this disease is also noted. We assess the challenges in diagnosis and the choice of treatment of this pathology in children and the effectiveness of surgical treatment disease.<br />Primary cardiac tumours are rare; vascular tumours and haemangiomas are rarer. The clinical picture of heart haemangioma is non-specific and varies as per its location and size. Echocardiography is the main diagnostic method for this disease. However, in most cases of preoperative diagnostic examination, the pre-surgery diagnosis is not confirmed. The final diagnosis of capillary haemangioma is established following immunohistochemical staining of the surgical material. Thus far, owing to the rare occurrence, a generally accepted tactic for the treatment of such patients with vascular heart tumours has not been developed.<br />This clinical case describes our experience of treating a rare pathology in children with unusual localisation as well as the rapid successful surgical removal of the tumour without complications and with a favourable post-surgery recovery period.</p><p>Received 14 May 2020. Revised 15 June 2020. Accepted 26 June 2020.</p><p><strong>Funding:</strong> The study did not have sponsorship.</p><p><strong>Conflict of interest:</strong> Authors declare no conflict of interest.</p><p><strong>Author contributions</strong> <br />Literature review: U.G. Kolbik, A.V. Gorustovich, Y.I. Linnik<br />Illustrations: U.G. Kolbik, I.V. Sakharov, V.V. Drozdovskaya <br />Drafting the article: U.G. Kolbik, A.V. Gorustovich, I.V. Sakharov<br />Critical revision of the article: I.V. Sakharov, M.M. Shved, Yu.I. Linnik<br />Surgical treatment: A.V. Gorustovich, M.M. Shved, U.G. Kolbik<br />Final approval of the version to be published: U.G. Kolbik, A.V. Gorustovich, Yu.I. Linnik, M.M. Shved, V.V. Drozdovskaya, <br />I.V. Sakharov, K.V. Drozdovski</p>

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