Despite a significant range of therapeutic measures employed to treat inflammatory diseases in the maxillofacial area, much of the effort falls short of effective suppression of the infection and proper regeneration as the outcome of the pathological process [1-6]. The development of optimal wound covering that would contribute to fast and complete recovery of the damaged structures appears an urgent issue in modern medicine. Scientific items, monographs and patents offer a wide range of materials used to create wound covering, with over 400 various types of sponges, films, combined collagen/gelatin/oxidized cellulose/starch-based implants, etc., described nowadays [7-10]. Of the well-known new-generation biodegradable synthetic and natural materials, a special place A B S T R A C T-A promising area in dentistry is the development of modern biotechnological wound dressings based on chitosan, which, depending on the molecular weight and three-dimensional structure, is able to change its physicomechanical properties from the state of a hydrogel to a dense frame structure with a different degree of swelling, and at the same time perform a depot function the drug introduced into it. Two new types of wound dressings based on chitosan with an immobilized 10% aqueous solution of iodopyrone were developed and their effectiveness was studied in an experiment on animals (rabbits) for dental practice. A comparative analysis was carried out with the well-known wound dressings Alvostaz, Gelatamp by introducing the studied samples into the well of the tooth after its extraction. The high efficiency of the proposed wound dressings based on chitosan was established.

Respiratory protective equipment (RPE) is in high demand during epidemics and pandemics. The SARS-CoV-2 pandemic has demonstrated that the global industry had insufficient capacity for providing people with high-efficiency respirators. In this context, it is important to assess the protective properties of equipment designed to prevent the spread of infections. In this review, the hydrodynamic and filtering characteristics of modern RPE types present in the market, as well as their consumer performance, are analyzed taking into account the properties of virus-bearing aerosols. Approaches to developing novel, more efficient fiber-based RPE are proposed.

Одним из важнейших аспектов регенеративной медицины является подбор матрикса — биологического каркаса тканеинженерной конструкции. Для наилучшей воспроизводимости структуры и свойств поврежденной ткани, а также поддержания клеточной адгезии и пролиферации оптимальным является использование матриксов, полученных при децеллюляризации нативных органов с последующей рецеллюляризацией различными клеточными линиями. Методами растровой электронной микроскопии в режиме естественной среды и сканирующей импульсной ультразвуковой микроскопии определена микроструктура нативных и децеллюляризированных матриксов дермальных тканей.

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